Cognitive empathy training for dementia caregivers

Effect of Cognitive Empathy Training on Dementia Caregivers

Not applicable Interventional Emory University · NCT06650527

This study tests whether teaching caregivers of people with dementia to better understand emotions can improve their mental health and reduce inflammation in their bodies.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment118 (estimated)
Ages50 Years and up
SexAll
SponsorEmory University Academic / other
Locations3 sites (Atlanta, Georgia and 2 other locations)
Trial IDNCT06650527 on ClinicalTrials.gov

What this trial studies

This project investigates the impact of cognitive empathy training on the mental health, inflammation, and immune function of caregivers for individuals living with dementia. The primary aim is to determine the effectiveness of this training in enhancing caregiver well-being and reducing inflammation. Additionally, the study will explore the psychological and neurobiological mechanisms that underlie these improvements. Caregivers will undergo pre and post-intervention assessments, including blood spot collection and MRI sessions, to evaluate changes resulting from the training.

Who should consider this trial

Good fit: Ideal candidates are caregivers living with their care recipient who have a high burden of care as indicated by a Zarit Burden Scale score of 19 or higher.

Not a fit: Patients who may not benefit include those with significant psychiatric illnesses, neurological disorders, or contraindications for MRI.

Why it matters

Potential benefit: If successful, this training could significantly improve the mental health and immune function of caregivers, leading to better care for individuals with dementia.

How similar studies have performed: Previous interventions aimed at supporting caregivers have shown benefits, particularly in enhancing coping skills, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Caregivers must live with their care recipient
* Caregivers must have a Zarit Burden Scale score of 19 or higher
* Caregivers must have no plans to move their care recipient to an institutional setting within the next year
* Caregivers must be able to read and write English
* Care recipient not in hospice
* Access to a mobile phone that can take and email photographs

Exclusion Criteria:

* Subjects with a history of seizures or other neurological disorders, alcoholism, or any other substance abuse
* Subjects with a history of psychiatric illness (excluding depression and anxiety disorders) will also be excluded
* Subjects with a history of head trauma based on Survey
* Subjects with MRI contra-indications

Where this trial is running

Atlanta, Georgia and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Caregivers of People Living With DementiaDementiaCognitive empathyPeople Living With DementiaCaregivers
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.