Cognitive behavioral treatments for insomnia in women with fibromyalgia

Impact of CBT for Insomnia on Pain Symptoms and Central Sensitization in Fibromyalgia

Not applicable Interventional University of Missouri-Columbia · NCT03744156

This study is testing two different sleep treatments to see if they can help women with fibromyalgia and insomnia sleep better and feel less pain.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment130 (estimated)
Ages18 Years and up
SexFemale
SponsorUniversity of Missouri-Columbia Academic / other
Locations1 site (Columbia, Missouri)
Trial IDNCT03744156 on ClinicalTrials.gov

What this trial studies

This clinical trial compares two cognitive behavioral sleep treatments in women diagnosed with fibromyalgia and insomnia. It aims to assess the impact of these interventions on sleep, pain, arousal, and brain function over an 8-week treatment period, with follow-ups at 6 and 12 months. By examining neural imaging outcomes, the study seeks to uncover the relationship between sleep disturbances and chronic pain, potentially leading to significant improvements in patient care for fibromyalgia sufferers.

Who should consider this trial

Good fit: Ideal candidates are women aged 18 and older who have been diagnosed with fibromyalgia and insomnia.

Not a fit: Patients with cognitive impairments, other sleep disorders, or those currently on medications affecting pain or sleep may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide effective non-pharmacological treatments to alleviate chronic pain and insomnia in women with fibromyalgia.

How similar studies have performed: Previous studies have shown promise in using cognitive behavioral interventions for insomnia, suggesting potential success for this approach in fibromyalgia patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* female
* 18+ years of age
* willing to be randomized
* can read and understand English
* diagnosed with Fibromyalgia and insomnia
* no prescript or over the counter pain or sleep medicaments for 1+ month

Exclusion Criteria:

* unable to provide informed consent
* cognitive impairment
* sleep disorder other than insomnia (i.e., sleep apnea, periodic limb movement disorder
* bipolar or seizure disorder
* other major psychopathology (other than depression or anxiety)
* psychotropic or other medications that alter pain or sleep
* participation in non-pharmacological treatment (including CBT) for pain, sleep, or mood outside current trial
* internal metal objects or electrical devices
* pregnancy

Where this trial is running

Columbia, Missouri

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions FibromyalgiaInsomniaChronic Widespread Pain
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.