Cognitive Behavioral Therapy for Depression and Medication Adherence in HIV/AIDS Patients

A Randomized Control Trial of Cognitive Behavioral Therapy on Adherence and Depression (CBT-AD) Among HIV/AIDS Patients on Follow up at Mattu Karl and Bedele Hospital, 2019

Not applicable Interventional Mattu University · NCT06109610

This study is testing whether Cognitive Behavioral Therapy can help adults with HIV/AIDS stick to their medication and feel less depressed.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment128 (estimated)
Ages18 Years and up
SexAll
SponsorMattu University Academic / other
Locations1 site (Addis Ababa)
Trial IDNCT06109610 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of Cognitive Behavioral Therapy (CBT) in improving medication adherence and reducing depression among patients living with HIV/AIDS. It addresses the high comorbidity of depression in this population, which negatively impacts adherence to antiretroviral therapy (ART) and overall health outcomes. The intervention combines CBT techniques specifically tailored for both depression and adherence counseling, aiming to enhance the quality of life and treatment efficacy for participants. The study will include adults aged 18 and older who are living with HIV/AIDS and have not previously undergone CBT.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who are living with HIV/AIDS and experiencing depression.

Not a fit: Patients who have previously undergone Cognitive Behavioral Therapy or those with acute physical or mental disturbances may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the mental health and treatment adherence of patients living with HIV/AIDS.

How similar studies have performed: Previous studies have shown that integrating CBT with adherence counseling can effectively improve both depression and medication adherence in similar populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* PLWHA who were 18 years old and above were included in the study

Exclusion Criteria:

* PLWHA who were previously took CBT and participants with acute physical or mental disturbances were excluded.

Where this trial is running

Addis Ababa

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions DepressionMedication Adherence
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.