CoGENES community genetic navigation training for Hispanic/Latino/a/x communities
Evaluation of a Colorectal Cancer Education Training Program
This project tests whether trained community engagement specialists can improve communication about colorectal cancer prevention and genetic testing for Hispanic/Latino/a/x adults in Los Angeles County.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 140 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Southern California Academic / other |
| Locations | 1 site (Los Angeles, California) |
| Trial ID | NCT07229443 on ClinicalTrials.gov |
What this trial studies
This randomized program enrolls Hispanic/Latino/a/x adults in Los Angeles County and compares a self-directed information packet versus a 45–60 minute CoGENES training delivered by community engagement specialists. Participants are randomized to review existing CRC prevention and genetic testing materials over 6–10 weeks or receive a single CoGENES training session, with the packet group offered optional training afterward. Study outcomes are collected by surveys at 8 weeks, 6 months, and 12 months to measure knowledge, communication, and engagement around genetic testing and CRC prevention. The CoGENES training is culturally tailored to language, literacy, numeracy, and Latino cultural values to prepare local lay navigators to respond to questions, fears, and barriers.
Who should consider this trial
Good fit: Hispanic/Latino/a/x adults aged 18 or older who reside in Los Angeles County, can read and speak English or Spanish, and are willing to sign informed consent are ideal candidates.
Not a fit: People under 18, those living outside Los Angeles County, individuals with major cognitive or psychiatric impairment, and those who already work as community health educators or had recent CRC/genetics training are unlikely to receive benefit from this program.
Why it matters
Potential benefit: If successful, this approach could increase culturally appropriate awareness, communication, and uptake of CRC screening and genetic testing among Hispanic/Latino/a/x communities.
How similar studies have performed: Prior work using community health workers and patient navigators has improved cancer screening and genetic testing uptake in some groups, but randomized, culturally tailored genetic navigation interventions specifically for Hispanic/Latino/a/x communities are still limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Must be 18 years of age or older * Ability to understand and the willingness to sign a written informed consent * Self-reported H/L ethnicity, of any race * Ability to read, write, and speak Spanish or English * Resides in Los Angeles County Exclusion Criteria: * Anyone younger than 18 years of age * Any person with major cognitive deficit or psychiatric impairment * Any person unable to read and write Spanish or English * Resides outside of Los Angeles County * Any person who considers themselves a community health educator or "promotor/a de salud" and/or has taken in the past three years training on colorectal cancer and/or cancer genetics
Where this trial is running
Los Angeles, California
- USC / Norris Comprehensive Cancer Center — Los Angeles, California, United States (Recruiting)
Study contacts
- Principal investigator: Mariana C Stern, PhD — University of Southern California
- Study coordinator: Bianca Rosales
- Email: Biancar@usc.edu
- Phone: 323-865-0811
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.