Cochlear implants and their effects on tinnitus symptoms
Effects of Cochlear Implantation on Tinnitus and Its Symptoms
This study is testing whether cochlear implants can help reduce tinnitus symptoms in people with hearing loss by using electrical stimulation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 16 Years to 90 Years |
| Sex | All |
| Sponsor | Chinese PLA General Hospital Academic / other |
| Locations | 1 site (Beijing, France) |
| Trial ID | NCT05453019 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of electrical stimulation from cochlear implants on tinnitus symptoms in patients with hearing loss. It aims to analyze changes in tinnitus loudness and frequency before and after cochlear implantation, as well as to explore the underlying mechanisms of how electrical stimulation may inhibit tinnitus. The research will also focus on optimizing stimulation parameters to enhance treatment efficacy. Participants will be monitored over an extended period to assess the long-term effects of the intervention.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 16 to 90 who have received cochlear implants and have experienced tinnitus for at least 0.25 years.
Not a fit: Patients with non-otogenic tinnitus or those with contraindications for cochlear implant surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a new therapeutic approach for managing tinnitus in patients with hearing loss.
How similar studies have performed: While there has been progress in using electrical stimulation for tinnitus treatment, this specific approach with cochlear implants is still under investigation and has not been widely tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\. This study included patients who received cochlear implants at the Auditory Implant Center of the Otorhinolaryngology-Head and Neck Surgery, China PLA General Hospital; * 2\. The patients ranged from 16 to 90 years old; * 3\. The patient experienced hearing loss and had either tinnitus longer than 0.25 years (experimental group 1) or no tinnitus (control group 2) before the cochlear implant surgery; * 4\. The cochlear implants accepted by patients included products from MED-EL, Cochlear, Advanced Bionics and Nurotron; * 5\. All patients voluntarily participated in the study. Exclusion Criteria: * 1 Tinnitus types exclude non otogenic tinnitus (including tinnitus caused by hypertension, heart disease, hyperthyroidism, neurasthenia, hyperlipidemia, etc.); * 2 Contraindications of cochlear implant surgery (refer to the guidelines for cochlear implant 2013 of the Chinese Medical Association); * 3 Intellectual deficiency
Where this trial is running
Beijing, France
- Qian Wang — Beijing, France, China (Recruiting)
Study contacts
- Study coordinator: Qian Wang, M.s.
- Email: only_elizabeth@126.com
- Phone: +8618211068103
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.