DeepTMS for chronic tinnitus using different H-coils

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, placebo-controlled trial exploring three treatment arms over two weeks: 18 Hz deepTMS with the H1 coil, 1 Hz deepTMS with the H4 coil, and 18 Hz placebo deepTMS with the H7 coil. Participants will be adults with chronic subjective tinnitus and a moderate tinnitus burden who meet safety criteria, recruited primarily from Regensburg. After screening, 60 participants will be randomized in equal groups, with outcome assessments including standard audiological measures and tinnitus-related questionnaires. The study also references a historical matched control group treated with a conventional rTMS protocol for comparison. Primary goal is to see if active deepTMS reduces tinnitus distress more than placebo and how the different coils compare.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Chronic tinnitus (\> 6 months)
* Moderate tinnitus burden-corresponding to a score of ≥ 18 on the Tinnitus Handicap Inventory
* Stable medication regimen with psychoactive substances

Exclusion Criteria:

* Objective tinnitus
* Severe and unstable internal medicine, neurological, and psychiatric comorbidities (particularly acute psychosis, severe depression, or substance dependence; epilepsy; brain tumor; encephalitis; history of traumatic brain injury)
* Presence of contraindications for TMS (electrical implants or metallic objects in the body, such as a pacemaker or insulin pump)
* Currently undergoing or planning to undergo tinnitus treatment during the study
* Meniere's disease, otosclerosis, acoustic neuroma, or other clear-cut or treatment-requiring causes of tinnitus

Where it's running

• Psychiatry and Psychotherapy, Center of Neuromodulation / TMS, University Regensburg
  Regensburg, Bavaria, Germany Recruiting

Study contacts

• Principal investigator: Stefan Schoisswohl, Prof. Dr. hum sc — Psychiatry and Psychotherapie University Regensburg
• Study coordinator: Stefan Schoisswohl, Prof. Dr.
• Email: stefan.schoisswohl@ukr.de
• Phone: +49 941 941 1284

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Deciding whether PTSD therapy or tinnitus therapy should come first for people with both conditions.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.