Clubhouse-based care for people with schizophrenia and related conditions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares a Clubhouse-model community rehabilitation approach to standard care for adults with schizophrenia spectrum or related disorders. Participants complete six visits over six months, including interviews, cognitive tests, and one MRI brain scan. The study aims to see if the Clubhouse model offers unique benefits for cognition and daily functioning. Procedures are non-invasive and include standardized cognitive assessments and brain imaging, with any risks described per standard MRI protocols. Eligibility focuses on adults 18-50 with stabilized medication and English fluency, excluding those with prior Clubhouse membership or certain comorbidities.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* (1) have a DSM-V diagnosis of schizophrenia, schizoaffective disorder, or schizophreniform confirmed by diagnostic assessment and medical record review
* (2) between the ages of 18-50
* (3) stabilized on psychotropic medication as indicated by no changes to the primary psychiatric medication in the last month
* (4) able to read and speak fluent English at a sixth grade level or higher for purposes of informed consent and cognitive testing
* For Clubhouse members, they must be a first-time, newly enrolled member

Exclusion Criteria:

* (1) had previous membership at a Clubhouse (Magnolia or elsewhere)
* (2) have a current severe substance use disorder
* (3) have persistent suicidal or homicidal behavior
* (4) a co-occurring diagnosis of an intellectual or learning disability or neurodevelopment condition (e.g., Autism; based on chart review)
* (5) had recent psychiatric instability requiring hospitalization in the past month;
* (6) history of a traumatic brain injury (TBI; based on record review)
* (7) contraindicators for MRI (e.g., pacemaker, claustrophobia)
* Participants in the usual care will be excluded if they are a current Clubhouse member or join a Clubhouse during participation in this research

Where it's running

• Case Western Reserve University
  Cleveland, Ohio, United States Recruiting

Study contacts

• Principal investigator: Jessica A Wojtalik, PhD — Case Western Reserve University
• Study coordinator: Jessica A Wojtalik, PhD
• Email: reach-study@case.edu
• Phone: 216-368-1329

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.