Clinical and radiographic outcomes after a fixed‑polyethylene posteriorly stabilized cemented total knee replacement with at least one‑year follow‑up
Official title: Study of the Clinical and Radiographic Results of a Fixed Polyethylene Posteriorly Stabilized Cemented Total Knee Prosthesis With a Minimum Follow-up of 1 Year.
Run by University Hospital, Strasbourg, France · NCT07313449 · Data updated 2026-11-12
This project tests how well a specific fixed‑polyethylene posteriorly stabilized cemented total knee replacement performs in adults who had the operation, using clinical and x‑ray data at least one year after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 960 (estimated) |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Status | Recruiting |
| Started | January 31, 2025 |
| Main results expected | February 2026 |
| Study ends | February 2026 |
| Registry record updated | January 2, 2026 |
| Trial ID | NCT07313449 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults who received the specified anatomic posteriorly stabilized cemented total knee prosthesis from Prof. F. Bonnomet between 2013 and 2024 and have complete preoperative, immediate postoperative, and ≥1‑year radiographic records.
✕Probably not a fit
Patients who had revision surgery during the follow‑up period for causes outside the study scope or who lack the required radiographic records are unlikely to benefit from inclusion.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a retrospective observational analysis of adult patients who underwent an anatomic, amplitude, posteriorly stabilized, fixed polyethylene, cemented total knee replacement by Professor F. Bonnomet at Strasbourg University Hospital between January 2013 and December 2024. Clinical records and radiographs from preoperative, immediate postoperative, and minimum one‑year follow‑up visits will be collected and analyzed for functional and radiographic outcomes. Results from this cohort will be described and compared with published literature on prosthesis alignment and outcomes to contextualize performance. The analysis focuses on implant alignment, radiographic integrity, and clinical outcomes over the short-to-medium term.
Why it matters
Potential benefit: If successful, this work could help surgeons and patients understand expected clinical and x‑ray outcomes after this specific knee implant and inform implant selection or surgical technique.
How similar studies have gone: Prior publications on knee prosthesis alignment and outcomes exist and provide comparative context, but direct reports on this exact implant and technique at this center are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patient * Patient who underwent total knee replacement (TKR) between January 2013 and December 2024 * Patient who underwent an Anatomic, Amplitude, posteriorly stabilized, fixed polyethylene, cemented TKR * Patient operated on by Professor F. Bonnomet * Available radiological data: preoperative, immediate postoperative, and postoperative at a minimum of 1 year follow-up Exclusion Criteria: \- Revision of the arthroplasty during the study follow-up period for a cause not investigated in the study
Where it's running
-
Service de Chirurgie Orthopédique et de Traumatologie du Membre Inférieur - CHU de Strasbourg - France
Strasbourg, France Recruiting
Study contacts
- Study coordinator: François BONNOMET, MD, PhD
- Email: Francois.bonnomet@chru-strasbourg.fr
- Phone: 33 3 68 76 52 82
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Ceramic hip resurfacing vs total hip arthroplasty for hip OA
This trial tests whether ceramic hip resurfacing helps people with hip OA walk farther each day than a modern total hip replacement.
-
Dexmedetomidine during hip replacement to modulate nerves and inflammation
A randomized, placebo-controlled study tests whether intravenous dexmedetomidine given during spinal anesthesia with a PENG nerve block can help regulate the body's stress and inflammatory response and improve recovery after hip replacement.
-
Preoperative Fasting to Shape the Gut with Hip Replacement
This trial tests whether a 20-day preoperative fasting plan can lower inflammatory signals and broaden gut microbes in adults undergoing total hip arthroplasty.
-
Cryoneurolysis for Chronic Pain: 6- and 12-Month Outcomes in Routine Care
This study tests whether cryoneurolysis, done as part of standard care for people with chronic pain, leads to meaningful improvements over 6 to 12 months.
-
Spinal anesthesia with intrathecal morphine vs PENG block (with or without dexamethasone) for hip replacement
In people aged 60 and older undergoing total hip arthroplasty, this study tests whether three anesthesia approaches provide better pain control and fewer side effects: spinal with intrathecal morphine, spinal with a PENG block, or spinal with a PENG block plus dexamethasone.
-
Intravenous dexamethasone for better pain control after hip replacement with a PENG block
This study tests whether giving dexamethasone through a vein, in 0, 4, or 8 mg doses, helps control pain after total hip arthroplasty when used with a PENG block.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.