CKD-MBD: Bone and Mineral Health in Adults with Advanced CKD

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort study examines adults with CKD stage 4-5 to explore how calcium, phosphate, parathyroid hormone, and other bone markers relate to kidney function and disease progression. It aims to identify factors associated with bone and cardiovascular outcomes in CKD-MBD and to generate hypotheses about underlying mechanisms. A sub-study will describe how calcium and phosphate balance interact with eGFR and how these relationships may inform future treatments and prevention. The work builds on the TMV framework for bone pathology in renal disease and uses routine clinical measurements to characterize associations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years
* CKD stage 4-5nonD (eGFR ≤ 29 ml/min) according to KDIGO (Kidney Disease Improving Global Outcome) definition

Exclusion Criteria:

* None

Where it's running

• Department of Nephrology, outpatient clinic, Herlev Hospital
  Herlev, Denmark Recruiting

Study contacts

• Study coordinator: Freja S Hassager, Medical doctor
• Email: freja.staehr.hassager.01@regionh.dk
• Phone: +4522554707

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.