Chiropractic care for inflammation and quality of life in people with HIV

The Effects of Chiropractic Care on Inflammation and Quality of Life in People Living With HIV

Not applicable Interventional Life University · NCT07466836

This pilot will test whether once-weekly chiropractic care can change blood inflammation markers and improve quality of life for adults living with HIV compared with no treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorLife University Academic / other
Locations1 site (Marietta, Georgia)
Trial IDNCT07466836 on ClinicalTrials.gov

What this trial studies

This is a pilot randomized controlled trial enrolling adults with medically confirmed HIV to test feasibility and explore clinical signals. Participants will be randomized to once-weekly chiropractic care or a no-treatment control and followed with online surveys and blood-derived immune marker measurements. The trial will measure feasibility outcomes (recruitment, retention, adherence) as well as changes in self-reported quality of life and inflammatory or immune lab markers. The work is conducted at Life University in Marietta, Georgia and is intended to inform a larger definitive trial if feasible.

Who should consider this trial

Good fit: Adults aged 18 or older with a medically confirmed HIV diagnosis who can complete online surveys, share lab results, and are willing to be randomized to weekly chiropractic care or no treatment are ideal candidates.

Not a fit: People already receiving regular chiropractic care, those with severe osteoporosis or a recent spinal fracture, or those enrolled in another HIV-related trial likely will not benefit or be eligible.

Why it matters

Potential benefit: If successful, this could offer a non-drug option that may improve quality of life and affect inflammation-related markers for people living with HIV.

How similar studies have performed: Applying chiropractic or manual therapies specifically to people with HIV is relatively novel: some small studies of manual therapies show benefits for pain and quality of life, but evidence on immune or inflammation effects in this population is limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged 18 or older
* Medically confirmed HIV diagnosis
* Willing to complete online surveys
* Willing to share lab results
* Willing to be randomized to either once weekly chiropractic care or a no treatment control condition

Exclusion Criteria:

* Participating in another clinical/behavioral trial related to HIV
* Receiving chiropractic care elsewhere
* Involved in litigation related to a physical, health-related injury
* Has severe osteoporosis or recent spinal fracture

Where this trial is running

Marietta, Georgia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Human Immunodeficiency VirusPilot ProjectsChiropracticRandomized Controlled Trial
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.