China health screening using low-dose chest CT to measure spine bone density and body/liver fat
Official title: China Nationwide Multi Center Big Data Study on the Quantitative Computed Tomography (QCT) and Health Status of Check -up Population
Run by Beijing Jishuitan Hospital · NCT03699228 · Data updated 2026-11-12
This project uses low-dose chest CT scans and QCT to test whether spine bone density, visceral fat, and liver fat can be measured in adults getting routine health checks across China.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 30 Years to 90 Years |
| Sex | All |
| Enrollment | 30000 (estimated) |
| Sponsor | Beijing Jishuitan Hospital Academic / other |
| Locations | 6 sites (Wuhu, Anhui and 5 other locations) |
| Status | Recruiting |
| Started | December 1, 2017 |
| Main results expected | June 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | August 17, 2025 |
| Trial ID | NCT03699228 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 30–90 undergoing low-dose chest CT for routine health checks at participating Chinese centers who are not pregnant and have no metal implants in the scan area.
✕Probably not a fit
People outside the 30–90 age range, pregnant women, or those with metal implants in the chest/scan area may not receive useful QCT measurements from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This nationwide, multi-center observational project collects low-dose chest CT raw data from health-check participants aged 30–90 at several Chinese hospitals. Investigators apply quantitative CT (QCT) processing to derive spinal bone mineral density, visceral adipose tissue volume, and liver fat content from existing CT data without additional scans. Pregnant women and people with metal implants in the scan area are excluded. The study will report how well QCT performs in the health-check setting and estimate the prevalence of osteoporosis, obesity, and liver steatosis in the screened population.
Why it matters
Potential benefit: If successful, routine low-dose chest CTs could also identify people with low bone density, excess visceral fat, or fatty liver so they can receive earlier follow-up and care.
How similar studies have gone: Previous opportunistic QCT analyses of routine CT scans have shown feasibility for measuring bone density, visceral fat, and liver fat in other cohorts, though large nationwide multi-center validation across China is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: health check subjects 30-90 years old low dose chest CT scan Exclusion Criteria: pregnant women metal implant in the CT scan area
Where it's running
-
Wu Hu Yijishan Hospital
Wuhu, Anhui, China Recruiting -
Beijing Jishuitan hospital
Beijing, Beijing Municipality, China Recruiting -
The first affiliated hospital of Guiyang Medical University
Guiyang, Guizhou, China Recruiting -
The first affiliated hospital of Zhengzhou University
Zhengzhou, Henan, China Recruiting -
Hua Shan hospital
Shanghai, Shanghai Municipality, China Recruiting -
Shanghai Ruijin hospital
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Principal investigator: xiaoguang cheng, MD — Beijing Jishuitan Hospital
- Study coordinator: xiaoguang cheng, md
- Email: xiao65@263.net
- Phone: 0086-010-58516947
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.