Checking for lymph node spread and tumor deposits in the posterior gastric mesentery after distal stomach cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study of patients who undergo distal gastrectomy with D2 lymphadenectomy plus complete mesogastric excision for gastric adenocarcinoma. Surgeons will resect the posterior gastric mesentery during the procedure and pathologists will examine the tissue for metastatic lymph nodes (including No.11p and part of No.11d) and tumor deposits. The number and distribution of positive nodes and any tumor deposits will be recorded and correlated with preoperative staging and clinical features. The study is single-center, conducted at the First Affiliated Hospital, Zhejiang University School of Medicine, and enrolls patients meeting defined inclusion and exclusion criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Aged older than 18 years and younger than 85 years
2. Primary gastric adenocarcinoma confirmed by preoperative pathology result
3. cT2-4N0-3M0 at preoperative evaluation according to the American Joint 8 Committee on Cancer (AJCC) Cancer Staging Manual 7th Edition
4. Patients who received distal gastrectomy with D2 lymphadenectomy plus complete mesogastric excision
5. American Society of Anesthesiologists (ASA) class I, II, or III
6. Written informed consent

Exclusion Criteria:

1. Negative preoperative biopsy
2. Too late tumour stage or metastasis (cT4b/M1)
3. BMI\>30 kg/m2
4. Total gastrectomy or proximal gastrectomy
5. previous neoadjuvant chemotherapy or radiotherapy
6. Previous upper abdominal surgery
7. Combined with other malignant diseases
8. Reject operation

Where it's running

• Department of Gastrointestinal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: Tao Wang, Ph.d
• Email: 15002740874@163.com
• Phone: +86-197-068-25286

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.