Check for undiagnosed PCD in adults with bronchiectasis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with CT-confirmed bronchiectasis will undergo nasal nitric oxide testing and analysis of nasal samples to identify undiagnosed primary ciliary dyskinesia. The study focuses on how often PCD is present but unrecognized in this population, acknowledging that many cases lack a clear cause. High-speed video microscopy analysis, a key diagnostic tool for PCD, is highlighted as part of the assessment approach. Results could improve targeted management and genetic counseling for affected patients. No comparator group or traditional randomized design is described in this protocol.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults (≥18) with CT-confirmed bronchiectasis

Exclusion Criteria:

* Pre-existing diagnosis of cystic fibrosis
* Pre-existing diagnosis of primary ciliary dyskinesia
* Inability to perform testing
* Refusal of consent

Where it's running

• Riley Hospital for Children
  Indianapolis, Indiana, United States Recruiting

Study contacts

• Study coordinator: Kenzie Mahan
• Email: krmahan@iu.edu
• Phone: 3172748899

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.