Characterizing patients and outcomes in severe tricuspid regurgitation

ChAracterization of Patients and Treatment OUtcomes in Severe Tricuspid Regurgitation

Observational Medical University of Warsaw · NCT06838611

This study looks at people with severe tricuspid regurgitation to see who can get a new heart valve treatment and how well it works for them.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorMedical University of Warsaw Academic / other
Locations1 site (Warsaw, Masovian Voivodeship)
Trial IDNCT06838611 on ClinicalTrials.gov

What this trial studies

This observational study aims to characterize patients eligible for transcatheter tricuspid valve interventions (TTVI) by enrolling individuals referred to tertiary-care centers for severe tricuspid regurgitation. The study will describe patient profiles, identify common reasons for disqualification from TTVI, and evaluate both the immediate and long-term efficacy and safety of the intervention. Participants will undergo standard qualification procedures followed by clinical examinations, echocardiography, and laboratory tests to monitor outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with severe tricuspid regurgitation who are being evaluated for transcatheter tricuspid valve intervention.

Not a fit: Patients with tricuspid regurgitation who are qualified for surgical treatment or have concomitant left heart valve disease may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the understanding of patient profiles and treatment outcomes for those with severe tricuspid regurgitation, potentially leading to better-targeted interventions.

How similar studies have performed: While this study focuses on a specific patient population and intervention, similar observational studies have shown promise in characterizing patient outcomes in valve disease interventions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* tricuspid regurgitation
* qualification for transcatheter tricuspid valve intervention

Exclusion Criteria:

* tricuspid regurgitation qualified for surgical treatment
* concomitant left heart valve disease qualified for surgical treatment
* multivessel coronary artery disease qualified for coronary artery bypass grafting
* lack of patient's consent to enter the registry

Where this trial is running

Warsaw, Masovian Voivodeship

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Tricuspid RegurgitationHeart FailureValve Heart Diseasetricuspid regurgitationtranscatheter tricuspid interventionstranscatheter edge-to-edge repairheart failure
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.