Ceribell EEG monitoring for adults in the ICU at high risk of delirium

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study that uses the Ceribell point-of-care EEG system to record EEG activity in adult ICU patients judged to be at high risk for delirium. Eligible patients are adults admitted to medical, surgical, or cardiovascular ICUs with an expected stay of at least 24 hours who are receiving support for shock or respiratory failure. Patients with structural head conditions preventing electrode placement, those already receiving continuous EEG for other clinical purposes, or those with prolonged prior mechanical ventilation are excluded. The primary goal is to measure how often EEG abnormalities are present in this high-risk ICU population and describe the recorded patterns.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patient ≥18 years old
* Requiring admission to a medical, surgical and/or cardiovascular ICU for an expected duration ≥ 24 hours
* Receiving treatment for shock (e.g., with vasopressors, intra-aortic balloon pump, or Extracorporeal Membrane Oxygenation therapy) and/or respiratory failure \[e.g., on mechanical ventilation or non-invasive positive pressure ventilation (NIPPV)\].

Exclusion Criteria:

* Any structural abnormality or head condition, including the presence of a device, that would prevent the use of the Ceribell EEG system for the entire anticipated EEG monitoring period. Examples include: Craniectomy with a missing bone flap in a region where Ceribell EEG electrodes would be placed.
* Anticipated use of continuous EEG for a purpose other than delirium detection during the entire expected monitoring period.
* Patients who have been on mechanical ventilation for \>72 hours within the current hospitalization or who are on long-term ventilator support prior to the injury that resulted in the current hospitalization.
* Expected death within 12 hours of enrollment or lack of commitment to treatment by family or the medical team (e.g., likely to withdraw life support measures within 12 hours of enrollment).
* Acute or chronic neurologic deficit precluding CAM-ICU assessments
* Inability to understand English
* Bilateral Deafness
* Blindness that will preclude delirium evaluation
* Current enrollment in a study that does not allow co-enrollment
* Inability to obtain informed consent
* Attending physician refusal
* Patient and/or surrogate refusal
* Patient unable to consent and no surrogate available
* Prisoners

Where it's running

• Vanderbilt University Medical Center
  Nashville, Tennessee, United States Recruiting

Study contacts

• Study coordinator: Michelle Hofmann, MSN
• Email: michelle.hofmann@ceribell.com
• Phone: 908-892-1193

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• VR-based sensory stimulation to prevent delirium in ICU patients

  This trial tests whether immersive virtual reality sensory stimulation can delay or reduce delirium in adult ICU patients compared with a non-immersive, tablet-based sensory experience.

  Recruiting Chinese University of Hong Kong · Shenzhen, Guangdong · NCT07806422

• Can family members spot delirium signs in ICU patients?

  Family members who know the patient well try a quick delirium check after visiting in the ICU, to see if their observations add information beyond routine nurse screenings.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07694687

• Digital and Plasma Biomarkers for Delirium in the ICU

  This study tests whether digital biomarkers and blood biomarkers can help detect and predict delirium in older adults in the ICU.

  Recruiting Scripps Health · La Jolla, California and 1 other locations · NCT07694206

• Therapeutic cuddling for critically ill children

  This project will try therapeutic cuddling to reduce pain, agitation, and delirium in children admitted to the pediatric intensive care unit.

  Recruiting University of Calgary · Calgary, Alberta · NCT07562048

• Ceribell Delirium Monitor Pilot in ICU Patients

  This pilot test uses the Ceribell Delirium Monitor in ICU patients to see if adding EEG-based delirium monitoring is feasible and how it might affect outcomes.

  Recruiting Ceribell Inc. · Irvine, California and 1 other locations · NCT07449416

• Impact of Family Presence on ICU Patient Outcomes

  This study looks at whether having family members present can help ICU patients need less medication, experience less confusion, spend fewer days on ventilators, and shorten their time in the ICU.

  Recruiting Istanbul University - Cerrahpasa · Istanbul · NCT06770751

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.