Care planning framework for older patients with advanced cancer

Feasibility and Acceptability of the ABC123 Framework for Advanced Cancer Care

Not applicable Interventional University of Colorado, Denver · NCT05408507

This study is testing a new care planning approach for older patients with advanced cancer to see if it helps them get the care they want and need.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment70 (estimated)
Ages60 Years and up
SexAll
SponsorUniversity of Colorado, Denver Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Aurora, Colorado)
Trial IDNCT05408507 on ClinicalTrials.gov

What this trial studies

This pilot study evaluates the feasibility and acceptability of the ABC123 care planning framework for older patients diagnosed with advanced, incurable cancer. The framework integrates principles from geriatrics, oncology, and palliative care to enhance care alignment with patient goals. Participants will undergo a series of assessments and follow-ups over six months, including physical performance evaluations and guided discussions about care goals. Feedback from patients and healthcare providers will be collected to assess the framework's implementation and impact on care delivery.

Who should consider this trial

Good fit: Ideal candidates are patients over 60 years old with recently diagnosed advanced, incurable solid-tumor cancer.

Not a fit: Patients with a different advanced cancer requiring systemic therapy or those with conditions compromising their well-being may not benefit from this study.

Why it matters

Potential benefit: If successful, this framework could improve the alignment of cancer care with the individual goals and values of older patients.

How similar studies have performed: While this approach is innovative, similar frameworks in geriatric oncology have shown promise in enhancing patient-centered care.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Provision to sign and date the consent form
2. Age \>65 years old, or \>60 with at least one deficit on a geriatric screen.
3. Stated willingness to comply with all study procedures and be available for the duration of the study
4. Diagnosis of a solid-tumor cancer that is not curable with surgery or radiation within the 6 mos. prior to consenting. And that would potentially be treated with systemic cytotoxic chemotherapy. If molecular marker status is pending for a particular tumor, patients may still be approached for enrollment in the study.
5. New patient consultation within the UCHealth Denver Metro system or newly diagnosed with recurrent metastatic/incurable disease
6. English speaking only for the pilot portion

Exclusion Criteria:

1. Have a diagnosis of a different advanced cancer that has required systemic therapy
2. Have any condition that, in the opinion of the investigator, would compromise the well-being of the subject or the study or prevent the subject from meeting or performing study requirements

Where this trial is running

Aurora, Colorado

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Advanced Cancerincurable cancergeriatric oncologygoals of care
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.