Cardiorespiratory interval training for post-stroke fatigue
Does a Cardiorespiratory Interval Training Program at Home Improve Post-stroke Fatigue?
This study is testing if a special cycling workout can help people who have recently had a stroke feel less tired.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Umeå University Academic / other |
| Locations | 1 site (Umeå) |
| Trial ID | NCT03458884 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of a structured cardiorespiratory interval training program on post-stroke fatigue in patients recently discharged from a stroke unit. Participants will be randomly assigned to either the intervention group, which will engage in a specific training regimen on an ergometer cycle, or a control group receiving standard early supported discharge care. The training consists of intervals of high-intensity cycling followed by active recovery, conducted three times a week for eight weeks. The primary outcome measured will be the change in fatigue levels as assessed by a standardized fatigue scale.
Who should consider this trial
Good fit: Ideal candidates are individuals who have experienced an acute stroke and are experiencing post-stroke fatigue, living independently in the Umeå or Gävle areas.
Not a fit: Patients with severe strokes, significant cardiac or pulmonary issues, or those living far from the study locations may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce post-stroke fatigue and improve recovery outcomes for stroke survivors.
How similar studies have performed: Previous studies have shown that interval training can improve cardiovascular fitness in various patient groups, including stroke survivors, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Preliminary or final diagnosis of acute stroke due to Brain infarction: large vessel disease, lacunar syndrome, cryptogenic stroke Intracerebral hemorrhage * Post-stroke fatigue (defined as a summation score of 28 or more on the S-FAS) * Medical stability * Independent living in Umeå or Gävle (in the nearby surrounding areas) and able to cycle an ergometer cycle. Exclusion Criteria: * Patients with severe stroke with modified Rankin Scale \>3 * Atrial fibrillation, pacemaker or other arrhythmia which exclude reliable monitoring of heart-frequency * Unstable pulmonary or cardiac disease * Serious co-morbidity with for example terminal cancer, hemodialysis, severe cognitive dysfunction with Montreal Cognitive Assessment (MOCA) ≤ 26 * Drug abuse * Patients living far away from the hospital or in residential care facilities.
Where this trial is running
Umeå
- Anna Bråndal — Umeå, Sweden (Recruiting)
Study contacts
- Principal investigator: Anna Bråndal, PhD — Department of Community Medicine and Rehabilitation, Physotherapy
- Study coordinator: Anna Bråndal, PhD
- Email: anna.brandal@umu.se
- Phone: +46702197609
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.