Cardiac-coherence breathing training for adults with Long COVID in Réunion

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults living in Réunion who meet the WHO definition of Long COVID and can document prior SARS‑CoV‑2 infection with a negative antigen test will be enrolled at CHU de la Réunion (Saint‑Denis and Saint‑Pierre). Participants will receive structured training in a cardiac coherence breathing technique (guided slow breathing to improve heart‑rate variability) as the interventional program. Symptom scores and functional outcomes will be recorded over time to measure change after the breathing program, with predefined exclusions for respiratory comorbidity, recent breathing‑technique practice, certain cardiac medications or devices, pregnancy, cognitive impairment, or guardianship. The intervention is non‑pharmacologic and delivered in an outpatient hospital setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients over the age of 18,
* living in Reunion and
* having a diagnosis of Long COVID according to the World Health Organization (WHO) definition will be included in this study.
* These patients must attest to their primary infection with Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and present a negative antigen test at the time of inclusion.

Exclusion Criteria:

Patients:

* with a chronic or disabling respiratory pathology preventing respiratory training (asthma, Chronic Obstructive Pulmonary Disease (COPD), active tuberculosis, pulmonary sequelae of COVID-19, etc.) practicing or having practiced a regular respiratory control technique (yoga, Cardiac coherence training, etc.) in the last 6 months
* taking a beta-blocker, betamimetic, anti-arrhythmic, morphine, antidepressant treatment (Escitalopram)
* having a pacemaker or severe heart disease
* Current and known pregnancy or breastfeeding woman
* with a cognitive deficit
* under guardianship/curators or under judicial protection

Where it's running

• CHU de la Réunion
  Saint-Denis, France Recruiting
• CHU de la Réunion
  Saint-Pierre, France Not yet recruiting

Study contacts

• Study coordinator: Léa BRUNEAU
• Email: lea.bruneau@chu-reunion.fr
• Phone: 02 62 90 68 83

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.