Cannabigerol Oil for Adolescents With ADHD

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, double-blind, placebo-controlled study in adolescents with ADHD. Sixty participants will be randomly assigned to receive either CBG oil or a matching placebo for a set period, with weekly dosing adjustments guided by a physician. The trial uses a parallel design to compare cognitive and behavioral outcomes between groups, alongside safety monitoring. Full-spectrum CBG oil is given sublingually at a starting concentration of 30 mg/mL, with individualized dosing based on tolerability and response. The study aims to determine whether CBG can provide additional benefits beyond standard ADHD therapies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adolescents aged 12 to 17 years
* Diagnosis of Attention-Deficit/Hyperactivity Disorder (ADHD) confirmed using the SNAP-IV (Swanson, Nolan and Pelham Questionnaire, version IV)
* History of previous treatment with pharmacological or non-pharmacological interventions without significant improvement of symptoms
* Absence of severe psychiatric disorders or relevant physical comorbidities
* Ability of the participant and legal guardian to understand study procedures
* Provision of written informed consent by the legal guardian and assent by the adolescent

Exclusion Criteria:

* Use of cannabinoid-based substances (natural or synthetic) within 30 days prior to study initiation
* History of intolerance or adverse reactions to cannabis-derived compounds (e.g., confusion, paranoia, pruritus, excessive drowsiness, vomiting, diarrhea, or seizures)
* Presence of any significant physical comorbidity
* Presence of severe psychiatric disorder not related to ADHD
* Moderate to severe cognitive impairment
* Inability or unwillingness to complete study procedures or questionnaires adequately

Where it's running

• Universidade do Sul de Santa Catarina - UNISUL
  Tubarão, Santa Catarina, Brazil Recruiting

Study contacts

• Study coordinator: Rafael Mariano Bitencourt, PhD
• Email: bitencourtrm@gmail.com
• Phone: +55 48 9 8833-6460

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.