Can virtual reality with hypnotic scripts ease dental anxiety during wisdom tooth removal?

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 18–65 with multiple wisdom teeth scheduled for extraction are randomized to receive either virtual reality using HypnoVR during the procedure or local anesthesia alone. The VR intervention provides immersive distraction combined with hypnotic scripting to reduce perioperative anxiety and postoperative pain. Outcomes focus on anxiety levels around the procedure and reported pain after extraction. The study is conducted at a single center in Strasbourg, France, led by University Hospital, Strasbourg, with standard anesthesia as the control. Participants must meet ASA I–II criteria and have no major contraindications to VR or the procedure.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Age 18-65
* Indication for extraction of 4 wisdom teeth or ≥2 mandibular wisdom teeth
* ASA I-II
* Written informed consent.

Exclusion criteria:

* Visual/hearing impairment
* Psychiatric disorders or psychotropics (\<8 weeks)
* Claustrophobia
* Heavy smoking \>10 cig/day
* Previous radiotherapy (jaw)
* ASA III-IV
* Pregnancy
* Antithrombotic therapy
* Chemotherapy
* Bisphosphonates
* Uncontrolled diabetes
* Severe anxiety requiring GA or pharmacological sedation
* No health insurance affiliation.

Where it's running

• Pierre KLIENKOFF
  Strasbourg, France Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.