Clinical trial Recruiting at 1 site Observational Ages 2 to 80

Burn Injury and Cellular Energy in Kids and Adults

Official title: The Role of the Mitochondrian in the Metabolic Stress Response to Burn Trauma

Run by Arkansas Children's Hospital Research Institute · NCT07643545 · Data updated 2026-11-12

This study tests how a burn injury affects cellular energy in patients admitted for burn care at Arkansas Children’s Hospital.

More Burn Injury trials

Quick facts

Study typeObservational
Ages2 Years to 80 Years
SexAll
Enrollment125 (estimated)
SponsorArkansas Children's Hospital Research Institute
Academic / other
Locations1 site (Little Rock, Arkansas)
StatusRecruiting
StartedApril 20, 2023
Main results expectedJune 2026
Study endsJune 2026
Registry record updatedJune 11, 2026
Trial IDNCT07643545 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are males or females aged 2–80 years admitted for burn care who can provide informed consent (or have an authorized representative).

Probably not a fit

Patients who are moribund at admission, unable to consent, or under 10 kg body mass may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will enroll patients aged 2 to 80 who require hospital admission for burn care at Arkansas Children’s Hospital. Researchers will collect basic demographic data, details of the burn, vital signs on the day of surgery, medications, and results from clinical tests. Biological samples such as blood, urine, and tissue obtained during surgeries will be analyzed to understand cellular energetics after burn injury. The study is sponsored by Arkansas Children’s Hospital Research Institute with collaboration from NIGMS and is conducted at a single center in Little Rock, AR.

Why it matters

Potential benefit: Gaining knowledge about how burns affect cellular energy could inform future approaches to improve recovery.

How similar studies have gone: Prior work in burn research has explored physiological responses; this study focuses on cellular energetics and is building on related observational data.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or Female
* Ages 2 years to 80 years
* Requiring hospital admission for burn care
* All races
* All ethnicities

Exclusion Criteria:

* Age \< 2 years
* Under 10 kg in body mass
* Age \> 80 years
* Active pregnancy
* Unable to provide informed consent and no legal authorized representative present
* Patient is considered moribund at the time of admission by the treating physician.

Where it's running

  • Arkansas Children's Hospital
    Little Rock, Arkansas, United States
    Recruiting

Study contacts

  • Principal investigator: Craig Porter, PhD — Arkansas Children's Research Institute
  • Study coordinator: Craig Porter, PhD
  • Email: cporter@uams.edu
  • Phone: 5013643340

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.