Burn Injury and Cellular Energy in Kids and Adults
Official title: The Role of the Mitochondrian in the Metabolic Stress Response to Burn Trauma
Run by Arkansas Children's Hospital Research Institute · NCT07643545 · Data updated 2026-11-12
This study tests how a burn injury affects cellular energy in patients admitted for burn care at Arkansas Children’s Hospital.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 2 Years to 80 Years |
| Sex | All |
| Enrollment | 125 (estimated) |
| Sponsor | Arkansas Children's Hospital Research Institute Academic / other |
| Locations | 1 site (Little Rock, Arkansas) |
| Status | Recruiting |
| Started | April 20, 2023 |
| Main results expected | June 2026 |
| Study ends | June 2026 |
| Registry record updated | June 11, 2026 |
| Trial ID | NCT07643545 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are males or females aged 2–80 years admitted for burn care who can provide informed consent (or have an authorized representative).
✕Probably not a fit
Patients who are moribund at admission, unable to consent, or under 10 kg body mass may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will enroll patients aged 2 to 80 who require hospital admission for burn care at Arkansas Children’s Hospital. Researchers will collect basic demographic data, details of the burn, vital signs on the day of surgery, medications, and results from clinical tests. Biological samples such as blood, urine, and tissue obtained during surgeries will be analyzed to understand cellular energetics after burn injury. The study is sponsored by Arkansas Children’s Hospital Research Institute with collaboration from NIGMS and is conducted at a single center in Little Rock, AR.
Why it matters
Potential benefit: Gaining knowledge about how burns affect cellular energy could inform future approaches to improve recovery.
How similar studies have gone: Prior work in burn research has explored physiological responses; this study focuses on cellular energetics and is building on related observational data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or Female * Ages 2 years to 80 years * Requiring hospital admission for burn care * All races * All ethnicities Exclusion Criteria: * Age \< 2 years * Under 10 kg in body mass * Age \> 80 years * Active pregnancy * Unable to provide informed consent and no legal authorized representative present * Patient is considered moribund at the time of admission by the treating physician.
Where it's running
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Arkansas Children's Hospital
Little Rock, Arkansas, United States Recruiting
Study contacts
- Principal investigator: Craig Porter, PhD — Arkansas Children's Research Institute
- Study coordinator: Craig Porter, PhD
- Email: cporter@uams.edu
- Phone: 5013643340
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.