Breathing practices to improve brain and mental health in adolescents

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an interventional feasibility project testing a structured breathing intervention delivered to adolescents recruited from two Mayo Clinic Health System outpatient pediatric and child/adolescent psychiatry clinics. The study will enroll patients from both rural and non-rural areas and track feasibility outcomes such as adherence, acceptability, and preliminary symptom change. Participants with current suicidal ideation, severe psychiatric comorbidities, or significant cognitive impairment are excluded. The intervention is nonpharmacologic and intended to be a low-risk adjunct to usual clinical care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adolescents between the ages of 12 and 17 who have been diagnosed with a major depressive disorder (mild or moderate) and/or an anxiety disorder.
* Participants may have co-occurring mild to moderate alcohol or drug use problems, provided these do not require immediate specialized treatment or crisis intervention.
* All participants must be receiving care at one of two participating MCHS outpatient psychiatry clinics and may reside in rural area (RUCA code 4-10) or non-rural area.
* Participants must be able to read and understand English, and both parental or guardian consent and adolescent assent will be required.

Exclusion Criteria:

* Current suicidal ideation or self-harm behavior requiring immediate clinical intervention
* Presence of severe psychiatric comorbidities such as psychosis, bipolar disorder, depression with psychotic features, severe alcohol and drug use, or eating disorders.
* Participants with significant cognitive impairment that would interfere with study participation.

Where it's running

• Mayo Clinic Health System-Albert Lea
  Albert Lea, Minnesota, United States Recruiting
• Mayo Clinic Health System-Eau Claire Clinic
  Eau Claire, Wisconsin, United States Recruiting

Study contacts

• Principal investigator: Pravesh Sharma — Mayo Clinic
• Study coordinator: Danielle Boos
• Email: boos.danielle@mayo.edu
• Phone: 715-464-8173

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.