Breathing exercises to reduce pain and improve recovery after transplant
Official title: Effect of Breathing Exercise on Pain and Quality of Recovery in After Transplantation Patients: A Randomized Controlled Trial
Run by Ankara Yildirim Beyazıt University · NCT07067580 · Data updated 2026-11-12
This project will try breathing exercises with adults aged 18–65 having their first transplant to see if they reduce pain and improve early recovery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Ankara Yildirim Beyazıt University Academic / other |
| Locations | 1 site (Ankara) |
| Status | Recruiting |
| Started | August 1, 2025 |
| Main results expected | March 31, 2026 |
| Study ends | April 30, 2026 |
| Registry record updated | December 15, 2025 |
| Trial ID | NCT07067580 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–65 undergoing their first elective transplant who are hemodynamically stable, able to perform the breathing maneuvers, and willing to provide informed consent.
✕Probably not a fit
Patients who are hemodynamically unstable, unable to safely perform breathing exercises, have early postoperative complications, are transferred to intensive care, or whose transplant was emergency/unplanned are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, nurse‑led interventional study teaches an experimental group breathing exercises the day before elective transplant surgery and asks patients to perform one set (four breaths) each hour during the first 24 postoperative hours. Vital signs will be recorded before and after each breathing exercise, pain scores will be collected at 0, 2, 6, 12, and 24 hours, and a recovery-quality scale will be applied on postoperative days 1 and 3. A control group will receive usual postoperative care without the structured breathing regimen. Patients who are hemodynamically unstable, have conditions that increase intra‑abdominal pressure, early complications, neurological or psychological problems, ICU transfer, or emergency/unplanned surgeries are excluded.
Why it matters
Potential benefit: If successful, this approach could reduce early postoperative pain and improve the quality of recovery in the first days after transplant.
How similar studies have gone: Similar nurse‑led breathing and respiratory physiotherapy programs have shown modest improvements in postoperative pain and recovery in other surgical populations, though evidence specifically after transplantation is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 and over, 65 and under, * Those who have had a transplant for the first time, * Patients who volunteer to participate in the study will be included in the study. Exclusion Criteria: * Hemodynamically unstable, * Those who may experience physical strain during breathing exercises and have a disease that may cause increased intra-abdominal pressure (e.g. bleeding hemorrhoids, hernias of all kinds, persistent cough, severe back pain, heart diseases, high blood pressure, urinary incontinence, epilepsy), * Those with early complications * Those with neurological or psychological problems, * Those who were transferred to the intensive care unit after surgery, * Emergency and unplanned cases will be excluded from the scope of the research.
Where it's running
-
Ankara Yıldırım Beyazıt University
Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Tuba Yilmazer, PhD
- Email: tyilmazer@aybu.edu.tr
- Phone: 5079552804
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.