Breath Booster respiratory training to strengthen breathing and improve life for people on hemodialysis

Effect of Breath Booster Training on Respiratory Muscle Strength and Quality of Life in Hemodialysis Patients

This trial will try a handheld Breath Booster breathing program to see if it strengthens breathing muscles and improves quality of life for people aged 50–60 who are on hemodialysis.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 50 (estimated)
• Ages: 50 Years to 60 Years
• Sex: All
• Sponsor: Cairo University (Academic / other)
• Locations: 1 site (Giza)
• Trial ID: NCT07183696 on ClinicalTrials.gov

What this trial studies

This interventional study tests a breathing-exercise program using the Breath Booster device in adults receiving hemodialysis. Fifty patients aged 50–60 with end-stage renal disease on hemodialysis for 1–3 years will be enrolled and perform guided respiratory training while clinical outcomes are measured. Primary outcomes include respiratory muscle strength and pulmonary function, and secondary outcomes include exercise capacity and health-related quality of life. Patients with diabetes, morbid obesity, severe chest disease, recent lung surgery, uncontrolled seizures, or significant sensory impairments are excluded.

Who should consider this trial

Good fit: Ideal candidates are adults 50–60 years old with end-stage renal disease receiving hemodialysis for 1–3 years who can follow instructions and do not have the listed exclusions.

Not a fit: Patients with diabetes, morbid obesity (BMI >35), severe chest diseases such as COPD or recent lung surgery, uncontrolled seizures, or significant hearing or visual impairments are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, the Breath Booster could strengthen respiratory muscles, increase exercise tolerance, and improve quality of life for hemodialysis patients.

How similar studies have performed: Previous studies of inspiratory muscle training in dialysis and chronic kidney disease populations have reported improvements in respiratory strength and functional capacity, though the Breath Booster device itself is less widely studied.

Eligibility criteria

Inclusion Criteria:

1. Fifty patients will be included in this study.
2. Their ages will range from 50 to 60 years.
3. Patients with end-stage renal disease (grade 5) receiving hemodialysis.
4. Patients on hemodialysis for around 1 to 3 years.
5. They will be able to follow instructions during evaluation and treatment.

Exclusion Criteria:

1. Diabetes Mellitus,
2. Morbid obesity with a BMI of more than 35 kg/m2.
3. Hearing or visual impairments.
4. Any severe chest diseases like COPD.
5. Certain contraindications for the use of the Breath Booster. Individuals with severe respiratory conditions such as unstable asthma, or emphysema, or those who have recently undergone lung surgery
6. Uncontrolled seizures.

Where this trial is running

Giza

• Faculty of physical therapy cairo university — Giza, Egypt (Recruiting)

Study contacts

• Study coordinator: Sameh Eldaly Sameh Eldaly

Conditions Hemodialysis