Clinical trial Recruiting at 1 site Interventional Ages 40 to 65

Box breathing added to short pulmonary rehabilitation for COPD breathlessness and exercise capacity

Official title: Additional Effects of Box Breathing Technique With Short Term Pulmonary Rehabilitation on Dyspnea and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease

Run by Foundation University Islamabad · NCT07518472 · Data updated 2026-11-12

This test will see whether adding box breathing to a short pulmonary rehabilitation program helps people aged 40–65 with mild COPD breathe easier and improve their functional capacity.

More Chronic Obstructive Pulmonary Disease trials

Quick facts

Study typeInterventional
Ages40 Years to 65 Years
SexAll
Enrollment40 (estimated)
SponsorFoundation University Islamabad
Academic / other
Locations1 site (Islamabad)
StatusRecruiting
StartedFebruary 28, 2026
Main results expectedMay 15, 2026
Study endsMay 15, 2026
Registry record updatedApril 8, 2026
Trial IDNCT07518472 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are men and women aged 40–65 with mild COPD (FEV1 ≥80% predicted) and mMRC dyspnea grade 1–3 who can follow instructions and participate in exercise.

Probably not a fit

Patients with severe COPD, recent acute exacerbations or active respiratory infections, significant orthopedic or neuromuscular limits, or inability to follow commands are unlikely to benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Forty participants with mild COPD will be assigned to two groups: short-term pulmonary rehabilitation with usual pharmacologic care, or the same program plus box breathing practice. The short-term program is delivered over a brief multi-week course to maximize feasibility and adherence. Outcomes will include measures of dyspnea, functional capacity, and quality of life collected before and after the intervention. The trial aims to identify any additional benefit from teaching a structured box breathing technique alongside standard rehabilitation.

Why it matters

Potential benefit: If successful, adding box breathing could reduce breathlessness and modestly improve exercise capacity and daily functioning for people with mild COPD.

How similar studies have gone: Pulmonary rehabilitation and many breathing exercises have demonstrated benefits for COPD, but the specific incremental effect of box breathing is relatively novel and has limited prior evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 40-65 years
* Both genders (male and female)
* Grade 1-3 on mMRC scale of dyspnea
* COPD mild stage according to global initiative for chronic obstructive lung -disease (GOLD) classification; Mild = FEV1 greater than or equal to 80% predicted

Exclusion Criteria:

* Patients having acute exerbation of COPD
* Patients diagnosed with acute infection (pmeumonia, T.B)
* Any orthopedic or neuromuscular condition that hinders participation in exercise training program
* Patients unable to follow command and instructions

Where it's running

  • Foundation University Islamabad
    Islamabad, Pakistan
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.