Box breathing added to short pulmonary rehabilitation for COPD breathlessness and exercise capacity

Additional Effects of Box Breathing Technique With Short Term Pulmonary Rehabilitation on Dyspnea and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease

NA · Foundation University Islamabad · NCT07518472

This test will see whether adding box breathing to a short pulmonary rehabilitation program helps people aged 40–65 with mild COPD breathe easier and improve their functional capacity.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages40 Years to 65 Years
SexAll
SponsorFoundation University Islamabad (other)
Locations1 site (Islamabad)
Trial IDNCT07518472 on ClinicalTrials.gov

What this trial studies

Forty participants with mild COPD will be assigned to two groups: short-term pulmonary rehabilitation with usual pharmacologic care, or the same program plus box breathing practice. The short-term program is delivered over a brief multi-week course to maximize feasibility and adherence. Outcomes will include measures of dyspnea, functional capacity, and quality of life collected before and after the intervention. The trial aims to identify any additional benefit from teaching a structured box breathing technique alongside standard rehabilitation.

Who should consider this trial

Good fit: Ideal candidates are men and women aged 40–65 with mild COPD (FEV1 ≥80% predicted) and mMRC dyspnea grade 1–3 who can follow instructions and participate in exercise.

Not a fit: Patients with severe COPD, recent acute exacerbations or active respiratory infections, significant orthopedic or neuromuscular limits, or inability to follow commands are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, adding box breathing could reduce breathlessness and modestly improve exercise capacity and daily functioning for people with mild COPD.

How similar studies have performed: Pulmonary rehabilitation and many breathing exercises have demonstrated benefits for COPD, but the specific incremental effect of box breathing is relatively novel and has limited prior evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 40-65 years
* Both genders (male and female)
* Grade 1-3 on mMRC scale of dyspnea
* COPD mild stage according to global initiative for chronic obstructive lung -disease (GOLD) classification; Mild = FEV1 greater than or equal to 80% predicted

Exclusion Criteria:

* Patients having acute exerbation of COPD
* Patients diagnosed with acute infection (pmeumonia, T.B)
* Any orthopedic or neuromuscular condition that hinders participation in exercise training program
* Patients unable to follow command and instructions

Where this trial is running

Islamabad

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Pulmonary Disease, Chronic Obstructive, COPD, Short term pulmonary rehabilitation, box breathing, dyspnea, functional capacity

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.