Clinical trial Recruiting at 1 site Interventional Ages 18 to 55

Bone marrow injection at the femoral neck fracture site in young adults with intracapsular hip fractures

Official title: Outcome of Bone Marrow Injection at Fracture Site in Intracapsular Fracture of Femoral Neck Treated by Head Preserving Surgery

Run by Idlib University · NCT07808294 · Data updated 2026-11-12

This study tests whether injecting the patient’s own bone marrow into a femoral neck fracture helps it heal faster and reduces avascular necrosis in adults aged 18–55 with certain fracture types.

More Femoral Neck Fractures trials

Quick facts

Study typeInterventional
Ages18 Years to 55 Years
SexAll
Enrollment32 (estimated)
SponsorIdlib University
Academic / other
Locations1 site (Idlib)
StatusRecruiting
StartedMay 12, 2025
Main results expectedMay 12, 2027
Study endsAugust 1, 2027
Registry record updatedSeptember 8, 2026
Trial IDNCT07808294 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults 18–55 with Garden type III or IV intracapsular femoral neck fractures treated within 24 hours of injury and suitable for fixation.

Probably not a fit

Patients with open fractures, polytrauma in shock/ICU, or those outside the 18–55 age range may not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study evaluates autologous bone marrow injection at the fracture site after anatomical reduction and fixation for intracapsular femoral neck fractures in young adults. The primary goals are to identify factors linked to these fractures and to see if bone marrow injection can promote complete healing, shorten recovery time, and lower avascular necrosis risk. Eligibility includes adults 18–55 with Garden type III or IV fractures within 24 hours of injury. The trial compares anatomical reduction with fixation alone versus reduction with fixation plus bone marrow injection. Conducted at Idlib University Faculty of Medicine, it aims to inform alternative strategies to minimize complications in a younger patient population.

Why it matters

Potential benefit: If successful, patients may experience faster fracture healing and a lower risk of avascular necrosis, potentially reducing the likelihood of needing later joint replacement.

How similar studies have gone: Previous approaches using autologous marrow or similar biologic strategies have shown mixed results; this study adds data on effectiveness in younger adults with specific fracture patterns.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 18 and 55 years.
* Intracapsular femoral neck fracture classified as Garden type III or IV.
* The time elapsed since the fracture occurred must not exceed 24 hours

Exclusion Criteria:

* Age under 18 years or over 55 years.
* Open femoral neck fracture.
* Neglected femoral neck fractures or fractures that occurred more than 24 hours prior to presentation.
* Polytrauma patients who are in shock or admitted to the intensive care unit (ICU).

Where it's running

  • Idlib university Faculty of medicine
    Idlib, Syria
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.