Bone marrow injection at the femoral neck fracture site in young adults with intracapsular hip fractures
Official title: Outcome of Bone Marrow Injection at Fracture Site in Intracapsular Fracture of Femoral Neck Treated by Head Preserving Surgery
Run by Idlib University · NCT07808294 · Data updated 2026-11-12
This study tests whether injecting the patient’s own bone marrow into a femoral neck fracture helps it heal faster and reduces avascular necrosis in adults aged 18–55 with certain fracture types.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 55 Years |
| Sex | All |
| Enrollment | 32 (estimated) |
| Sponsor | Idlib University Academic / other |
| Locations | 1 site (Idlib) |
| Status | Recruiting |
| Started | May 12, 2025 |
| Main results expected | May 12, 2027 |
| Study ends | August 1, 2027 |
| Registry record updated | September 8, 2026 |
| Trial ID | NCT07808294 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 18–55 with Garden type III or IV intracapsular femoral neck fractures treated within 24 hours of injury and suitable for fixation.
✕Probably not a fit
Patients with open fractures, polytrauma in shock/ICU, or those outside the 18–55 age range may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study evaluates autologous bone marrow injection at the fracture site after anatomical reduction and fixation for intracapsular femoral neck fractures in young adults. The primary goals are to identify factors linked to these fractures and to see if bone marrow injection can promote complete healing, shorten recovery time, and lower avascular necrosis risk. Eligibility includes adults 18–55 with Garden type III or IV fractures within 24 hours of injury. The trial compares anatomical reduction with fixation alone versus reduction with fixation plus bone marrow injection. Conducted at Idlib University Faculty of Medicine, it aims to inform alternative strategies to minimize complications in a younger patient population.
Why it matters
Potential benefit: If successful, patients may experience faster fracture healing and a lower risk of avascular necrosis, potentially reducing the likelihood of needing later joint replacement.
How similar studies have gone: Previous approaches using autologous marrow or similar biologic strategies have shown mixed results; this study adds data on effectiveness in younger adults with specific fracture patterns.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 55 years. * Intracapsular femoral neck fracture classified as Garden type III or IV. * The time elapsed since the fracture occurred must not exceed 24 hours Exclusion Criteria: * Age under 18 years or over 55 years. * Open femoral neck fracture. * Neglected femoral neck fractures or fractures that occurred more than 24 hours prior to presentation. * Polytrauma patients who are in shock or admitted to the intensive care unit (ICU).
Where it's running
-
Idlib university Faculty of medicine
Idlib, Syria Recruiting
Study contacts
- Study coordinator: Mohamad M ISSA, MD
- Email: mohamadalessa888@gmail.com
- Phone: 0954233150
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.