Blood test to predict postpartum depression in pregnant women
Clinical Validation of a Predictive Test for Postpartum Depression
University of Virginia · NCT06831968
This study is testing a blood test to see if it can predict postpartum depression in pregnant women during their third trimester.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | University of Virginia (other) |
| Locations | 2 sites (Charlottesville, Virginia and 1 other locations) |
| Trial ID | NCT06831968 on ClinicalTrials.gov |
What this trial studies
This observational study aims to develop and validate a blood test that may predict postpartum depression (PPD) in pregnant women. Up to 500 participants will be recruited from the University of Virginia, focusing on those in their third trimester of pregnancy. The study will assess the accuracy of the test by determining the rates of true and false positives and negatives for PPD outcomes up to six months postpartum. Participants will not receive their individual test results, as the test is investigational and not yet FDA approved.
Who should consider this trial
Good fit: Ideal candidates are pregnant women aged 18 or older with a singleton pregnancy who are less than 30 weeks' gestation.
Not a fit: Patients who are not pregnant or those with multiple pregnancies may not benefit from this study.
Why it matters
Potential benefit: If successful, this test could help identify women at risk for postpartum depression, allowing for earlier intervention and support.
How similar studies have performed: While this approach is investigational, similar studies exploring predictive tests for postpartum depression have shown promise, but this specific test is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * subject must be pregnant (singleton pregnancy) * \<30 weeks' gestation, age 18 or above * able to provide written consent in English Exclusion Criteria: * The study team and/or PI may exclude anyone deemed unsafe to participate in the protocol.
Where this trial is running
Charlottesville, Virginia and 1 other locations
- University of Virginia — Charlottesville, Virginia, United States (RECRUITING)
- Inova Health System — Falls Church, Virginia, United States (RECRUITING)
Study contacts
- Principal investigator: Jennifer L Payne, MD — University of Virginia
- Study coordinator: Meeta Pangtey, MPH
- Email: uwp7jh@uvahealth.org
- Phone: 434-987-7367
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Postpartum Depression, Pregnancy, Predictive Test, Blood Test, Third Trimester