Blood test for managing colorectal cancer screening
Exploratory Study of the Relevance of a Blood Test in the Management of Patients in the Context of Colorectal Cancer Screening
This study is testing a blood test to see if it can help manage colorectal cancer screening for adults who have a positive test or have been diagnosed with cancer and need surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de Besancon Academic / other |
| Locations | 3 sites (Besançon and 2 other locations) |
| Trial ID | NCT04767568 on ClinicalTrials.gov |
What this trial studies
This study explores the relevance of a blood test in the management of patients undergoing colorectal cancer screening. It focuses on individuals aged 18 and older who either have a positive immunological test indicating potential colorectal cancer or have already been diagnosed with adenocarcinoma and are candidates for surgery. The study aims to improve early detection and management of colorectal cancer, especially in light of delays caused by the COVID-19 pandemic. Participants will provide blood samples, tumor tissue, and stool collections to assess the effectiveness of the blood test.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 with suspected colorectal cancer from a positive screening test or those already diagnosed with adenocarcinoma awaiting surgery.
Not a fit: Patients who are minors, pregnant, or unable to comply with the study protocol will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance early detection of colorectal cancer, leading to timely interventions and improved patient outcomes.
How similar studies have performed: While the use of blood tests for cancer detection is an emerging field, this specific approach in colorectal cancer screening is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged more than18 years * Cohort A : patients with suspected colorectal cancer following a positive immunological test during screening (presence of blood detected in the stool) or with gross bleeding OR Cohort B : patients who have already performed colonoscopy (on symptoms, or because of family history, or other ...), for whom the diagnosis of adenocarcinoma was identified by pathology prior to surgery, candidates for surgery on their colorectal tumor * Signed and dated informed consent * Patient affiliated to or beneficiary of French social security system. Exclusion Criteria: * Vulnerable persons according to the law (minors, adults under protection, persons deprived of liberty ...) * Not ability to comply with the study protocol, in the Investigator's judgment * pregnant woman * Patient in the period of exclusion of another study
Where this trial is running
Besançon and 2 other locations
- CHU de Besançon — Besançon, France (Recruiting)
- Hôpital Nord-Franche-Comté — Montbéliard, France (Not_yet_recruiting)
- Centre Hospitalier Intercommunal de Haute-Saône — Vesoul, France (Not_yet_recruiting)
Study contacts
- Study coordinator: Christophe BORG, Pr
- Email: christophe.borg@efs.sante.fr
- Phone: +33381668166
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.