Blood test for early diagnosis of colorectal cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to develop and validate a blood test that combines molecular markers in plasma with risk factors and clinical data to improve early diagnosis of colorectal cancer and advanced adenomas. It involves a multicenter, case-control design where patients undergoing colonoscopy or surgical resection will be compared to healthy individuals. The goal is to create an optimized algorithm that enhances the accuracy of early detection.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients over the age of 18 who are able to understand the participant information and sign the informed consent.
* Patients who are going to undergo colonoscopy or surgical resection for tumor (CRC).

Exclusion Criteria:

* Patients who had developed any type of cancer in the 5 years prior to their participation in this study.
* Patients who have received previous chemotherapy or radiotherapy.
* Patients diagnosed with non-advanced adenomas, serrated polyps, Familial Adenomatous Polyposis or Lynch Syndrome.
* Patients with inadequate bowel preparation for colonoscopy.
* Patients who have undergone colonoscopy/polipectomy in the previous 5 years.
* Patients with hemolyzed plasma.

Where it's running

• Hospital Clinico Universitario Lozano Blesa
  Zaragoza, Aragon, Spain Recruiting
• Hospital Universitario de Cruces
  Bilbao, Basque Country, Spain Recruiting
• Hospital Universitario de Salamanca
  Salamanca, Castille and León, Spain Recruiting
• Hospital Centro Médico de Asturias
  Oviedo, Principality of Asturias, Spain Recruiting
• Policlinica Gipuzkoa Hospital
  Donostia / San Sebastian, Basque Country, Spain Completed
• Hospital Universitario Marques de Valdecilla
  Santander, Cantabria, Spain Terminated

Study contacts

• Study coordinator: Marta Jimenez
• Email: mjimenez@amadix.com
• Phone: +34637899149

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.