Clinical trial Recruiting at 1 site Interventional Ages 65 and up

Blood Flow Restriction Training for older adults in acute rehabilitation

Official title: Blood Flow Restriction Training in Acute Geriatric Rehabilitation: A Randomized Controlled Trial on Its Effects and Safety in Hospitalized Older Adults.

Run by University Hospital, Bonn · NCT07291765 · Data updated 2026-11-12

This trial tests whether blood flow restriction training on a stationary bike can help improve muscle mass and general health in people over 65 during two weeks of acute geriatric rehabilitation after hip-related injury.

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Quick facts

Study typeInterventional
Ages65 Years and up
SexAll
Enrollment90 (estimated)
SponsorUniversity Hospital, Bonn
Academic / other
Locations1 site (Cologne, North Rhine-Westphalia)
StatusRecruiting
StartedJanuary 1, 2026
Main results expectedDecember 31, 2026
Study endsMarch 31, 2027
Registry record updatedOctober 5, 2026
Trial IDNCT07291765 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 65 in acute geriatric rehabilitation after a hip fracture, able to participate in stationary cycling five days a week for two weeks.

Probably not a fit

Patients with contraindications to blood flow restriction or severe vascular or thrombotic conditions may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial compares blood flow restriction (BFR) training to sham-BFR training in adults aged 65 and older undergoing acute geriatric rehabilitation after a hip fracture. Participants ride a stationary bike five times per week for two weeks while the intervention group uses BFR and the control group uses a sham procedure. Outcomes focus on feasibility and changes in general health and muscle-related measures. The study is conducted at St. Marien Hospital Köln with University Hospital Bonn as the lead sponsor. Recruitment targets patients hospitalized for two weeks post-fracture in a geriatric rehabilitation setting.

Why it matters

Potential benefit: If successful, BFR training could offer a safer way to improve muscle strength and health in older adults undergoing rehabilitation.

How similar studies have gone: Prior research suggests BFR may be effective in similar populations, but application in acute geriatric rehabilitation remains exploratory.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults \>65 years with a two week hospitalized acute rehabilitation after a fracture closed to the hip joint

Exclusion Criteria:

* Sickle Cell Anemia
* Iatrogenic changes of the vessels at the place of the tournqiuet application (e.g. Stents)

Where it's running

  • St. Marien-Hospital Köln
    Cologne, North Rhine-Westphalia, Germany
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.