Blended (online + in-person) versus face-to-face transdiagnostic group therapy for anxiety and depression
Official title: Efficacy of a Group Treatment Based on Transdiagnostic Perspective for Emotional Disorders and Applied in Blended Format: a Randomized Controlled Trial.
Run by Universitat Jaume I · NCT05569018 · Data updated 2026-11-12
This trial will try whether a blended program (online modules plus group sessions) helps adults with anxiety or depression as much as traditional face-to-face group therapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 144 (estimated) |
| Sponsor | Universitat Jaume I Academic / other |
| Locations | 1 site (Castellon, Castellón) |
| Status | Recruiting |
| Started | November 23, 2024 |
| Main results expected | July 2027 |
| Study ends | July 2027 |
| Registry record updated | May 5, 2026 |
| Trial ID | NCT05569018 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with a DSM-5 emotional disorder ( anxiety or depressive disorders), who understand Spanish, have Internet access and an email address, and can commit to group sessions without concurrent psychological treatment or major medication increases are ideal candidates.
✕Probably not a fit
Patients with severe mental disorders (psychosis, bipolar disorder), substance dependence, high suicide risk, serious medical conditions preventing participation, lack of Spanish fluency, or no internet access are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a two-arm, parallel-group randomized controlled trial comparing a blended group transversal protocol (online content combined with group sessions) to a fully face-to-face group transversal protocol for emotional disorders. Adults meeting DSM-5 criteria for anxiety or depressive disorders will be randomly assigned to one of the two interventions and followed through treatment. Primary outcomes include changes in clinical symptom measures, along with retention, dropout, adherence, and acceptability; the study will also examine mediators and moderators of treatment effect. The interventions use a transdiagnostic cognitive-behavioral approach delivered in group format to improve scalability and cost-effectiveness.
Why it matters
Potential benefit: If successful, this could offer a more convenient and cost-effective therapy option that works as well as standard in-person group CBT for emotional disorders.
How similar studies have gone: Transdiagnostic CBT, group CBT, and blended CBT have each shown positive results in prior research, but combining a transdiagnostic protocol with a blended group format is novel and has not been previously tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being 18 years old or more. * DSM-5 (APA, 1013) diagnostic criteria for emotional disorder (panic disorder, agoraphobia, social anxiety disorder, generalized anxiety disorder, major depressive disorder, dysthymia, obsessive-compulsive disorder, non-specified anxiety disorder, non-specified depressive disorder). * Good understanding of Spanish. * Access to the Internet and email address. * Informed consent to participate. Exclusion Criteria: * Diagnosis of a severe mental disorder (psychotic disorder, bipolar disorder, substance and/or alcohol dependence). * High risk of suicide. * Having a serious medical illness or other condition that prevents treatment from being carried out. * Receiving another psychological treatment during the study period. * Changes and/or increases in pharmacological treatment during the study period (a decrease is accepted).
Where it's running
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Jaume I University, Castellón, Spain
Castellon, Castellón, Spain Recruiting
Study contacts
- Principal investigator: Amanda Díaz-García, Dr. — University of Zaragoza, Teruel Campus
- Study coordinator: Juana María Bretón-López, Dr.
- Email: breton@uji.es
- Phone: +34 964387642
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.