Biomarkers in the Heat and Moisture Exchange Filter during Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates if proteins and small biological particles from a patient’s exhaled air are present in the HME filter used during elective surgery with invasive ventilation. The focus is on exhaled breath proteomics gathered from the filter to understand potential biological material captured by the device. Eligible adults undergoing non-malignant surgery under anesthesia with planned mechanical ventilation are included, with analysis limited to routine clinical practice. The study does not introduce new treatments and builds on standard perioperative care at Aalborg University Hospital. No interventions are assigned; data are collected from routine care materials for research purposes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ≥18 years, able to understand study information in Danish.
* Admitted for elective surgery for non-malignant conditions with either intravenous or inhalation anaesthesia and invasive mechanical ventilation according to standard practice.
* Expected invasive mechanical ventilation \> 1 hour.
* Possess legal capacity.
* Informed, signed consent is obtained.

Exclusion Criteria:

* Patients who are transferred to the ICU for continuous invasive mechanical ventilation after end of elective surgery.
* Known chronic lung disease.

Where it's running

• Aalborg University Hospital
  Gistrup, Denmark Recruiting

Study contacts

• Study coordinator: Inger L Gade, PhD
• Email: inlg@rn.dk
• Phone: +45 20843941

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.