Biobank for monitoring and understanding Huntington's disease
HD Project: Neurodegenerative Disease Research Platform - Novel Remote Monitoring and Deep Phenotyping.
Stanford University · NCT06941662
This study is trying to find new ways to track Huntington's disease by using home monitoring and tests to see how it changes over time for people living with the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Sex | All |
| Sponsor | Stanford University (other) |
| Locations | 1 site (Palo Alto, California) |
| Trial ID | NCT06941662 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on identifying new biomarkers for Huntington's disease by combining remote monitoring techniques with fluid biomarker analysis. Participants will engage in video-based assessments and mobile app cognitive tests, with data analyzed using machine learning algorithms to track disease progression. The study aims to develop individualized markers that can be monitored at home, correlating digital assessments with changes in biological samples. Participants will have one in-person visit annually and remote check-ins every three months.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals who have tested positive for the Huntington's disease expansion mutation.
Not a fit: Patients with movement disorders who do not have a positive test for the Huntington's disease expansion mutation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and understanding of Huntington's disease, enhancing patient care and treatment options.
How similar studies have performed: Other studies utilizing remote monitoring and machine learning for neurological conditions have shown promise, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals with a positive test for the HD expansion mutation. Exclusion Criteria: * Individuals with movement disorders with a negative test for the HD expansion mutation.
Where this trial is running
Palo Alto, California
- Stanford University — Palo Alto, California, United States (RECRUITING)
Study contacts
- Principal investigator: Kyan Younes, MD — Stanford University
- Study coordinator: Minhtrang Chu, Study Coordinator
- Email: mtchu@stanford.edu
- Phone: 650-250-3160
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Huntington Disease, Huntington's disease biomarkers, remote monitoring, biobank, observational study