BFR resistance training vs BFR cycling for knee pain in athletes with patellofemoral pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, single-blind trial compares two blood flow restriction (BFR) training modalities in 60 athletes aged 18-40 with patellofemoral pain syndrome. Group A performs BFR resistance training (leg press and seated knee extension at 30% 1RM) 3 times weekly, while Group B does BFR cycling with low resistance under similar supervision. Both groups receive limb occlusion at 80% of limb occlusion pressure during sessions over 8 weeks, with outcomes measured at baseline and week 8, including pain (NPRS), quadriceps strength, and Kujala knee function. Data will be analyzed using appropriate within- and between-group tests to determine differences in pain, strength, and functional outcomes. The study aims to determine if one BFR modality offers superior symptom relief or functional gains for athletes with PFP.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Male and female athletes aged 18-40 years
2. Clinically diagnosed with patellofemoral pain syndrome
3. Anterior or retropatellar knee pain of at least 3 months duration
4. Pain provoked by at least two functional activities (e.g., squatting, stair climbing, running, prolonged sitting)
5. Willingness to participate and provide written informed consent

Exclusion Criteria:

1. History of knee surgery or significant knee trauma in the past 6 months
2. Presence of ligament, meniscal, or cartilage injuries
3. Neurological, vascular, or systemic inflammatory conditions
4. Contraindications to BFR training (e.g., deep vein thrombosis, uncontrolled hypertension)
5. Pregnancy

Where it's running

• Ibadat International University, Islamabad (Iiui)
  Islamabad, Pakistan Recruiting

Study contacts

• Principal investigator: Hafsah Gul Khattak, DPT, MS-NMPT — Ibadat International University, Islamabad (Iiui)
• Study coordinator: Haroon Khan, MS. Sports Physical Therapy
• Email: haroonkhan2k00@gmail.com
• Phone: +923000526711

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.