Active release and myofascial release for patellofemoral knee pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will compare groups receiving active release therapy plus myofascial release to standard care for patellofemoral pain. Participants are aged 15-40 with at least three months of retro patellar pain. The study will be conducted at Riphah Rehabilitation Clinic and Ghurki Trust Hospital in Lahore, using consecutive sampling to enroll 30 subjects. Outcomes will include pain, range of motion, and functional knee performance. The trial aims to determine if targeted soft tissue techniques can improve symptoms and function in PFPS patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Experience retro patellar pain for at least three months, including pain at rest or during activities such as ascending or descending stairs, jumping, running, squatting, kneeling, or prolonged sitting (12).
* Patients with + ive Squat test in the absence of any pathology
* Patients also must have presented with an insidious onset of symptoms unrelated to trauma and a positive Clark test (19).
* Reduced knee range of motion, especially extension

Exclusion Criteria:

* A history of significant lower extremity, pelvic, or spinal surgery/fracture, or traumatic lesions of ligaments or meniscus within the past six months.
* Presence of other orthopedic conditions (e.g., ACL rupture, meniscal tears), neurological disorders (e.g., multiple sclerosis, paralysis), rheumatological diseases (e.g., rheumatoid arthritis, ankylosing spondylitis), or congenital conditions leading to osteoarthrosis.
* Current pregnancy
* A history of connective tissue disease, patellofemoral dislocation or subluxation, osteoarthrosis of the knees.

Other forms of anterior knee pain (e.g., Osgood-Schlatter disease, tendon pain, bursitis). A history of referred pain from the lumbar spine (12). or

Where it's running

• Riphah Rehabilitation Clinic
  Lahore, Punjab Province, Pakistan Recruiting

Study contacts

• Principal investigator: Syed Shakil ur Rehman, PhD — Riphah International University
• Study coordinator: Syed Shakil ur Rehman, PhD
• Email: shakil.urrehman@riphah.edu.pk
• Phone: +92 320 786661

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Telerehabilitation vs. supervised rehabilitation for patellofemoral pain syndrome

  This study tests whether remote exercise therapy can work as well as in-person supervised rehab for people with patellofemoral pain.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT07921212

• Kinesio Taping vs McConnell Taping for Patellofemoral Pain: Adding Taping to a Hip-Knee Exercise Program

  This study tests whether Kinesio or McConnell taping, when added to a standardized hip-knee exercise plan, helps people 18–50 with patellofemoral pain more than exercise alone.

  Recruiting Cairo University · Beirut, Beirut · NCT07671482

• BFR resistance training vs BFR cycling for knee pain in athletes with patellofemoral pain

  A 8-week randomized trial tests whether low-load blood flow restriction resistance training or low-resistance BFR cycling better reduces knee pain and improves leg strength and function in athletes with patellofemoral pain.

  Recruiting Ibadat International University, Islamabad · Islamabad · NCT07585305

• Online education for knee pain management before physiotherapy

  This study is testing whether an online education program can help people with knee pain learn to manage their condition better while they wait for physiotherapy.

  Recruiting East Suffolk and North Essex NHS Foundation Trust · Colchester · NCT06744257

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.