Better quality-of-life questions for adolescents and young adults with cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project refines PROMIS patient-reported outcome items focused on body image, fertility, and financial burden for adolescents and young adults with cancer. It applies item response theory analyses to test assumptions like unidimensionality and local independence, examines item-level properties including differential item functioning, and supports development of computer-adaptive testing. Participants (AYA cancer patients/survivors, AYA general-population peers, and caregivers) complete surveys and legacy measures to allow creation of short forms and to test convergent validity. The work is coordinated through Wake Forest Baptist Comprehensive Cancer Center with NCI collaboration and is limited to English-speaking participants in the U.S.

Why it matters

Who can join: the full rules

AYAs with a cancer history (AYA-C)

Inclusion Criteria:

* Young adults between the ages of 15 to 39 years;
* First diagnosed with cancer during 15 to 39 years of age;
* Able to read and understand English;
* Live in the United States;
* Have a new cancer diagnosis and are receiving curative treatment OR are currently 0 to 10 years post-treatment.

Exclusion Criteria:

* Diagnosed with basal cell skin cancer; or
* Are currently receiving hospice care.

AYAs General Population (AYA-GP)

Inclusion Criteria:

* Young adults between the ages of 15 to 39 years;
* Able to read and understand English; and
* Live in the United States.

Caregivers of AYAs with cancer (AYA-Cg)

Inclusion Criteria:

* 18 years of age or older;
* Able to read and understand English;
* Live in the United States;
* Have a child/ward/partner for whom they have provided care, AND
* Their child/ward/partner is 15 to 25 years of age and meets the other eligibility criteria as an AYA participant with a cancer history (described above).

Where it's running

• Wake Forest Baptist Comprehensive Cancer Center
  Winston-Salem, North Carolina, United States Recruiting

Study contacts

• Principal investigator: John Salsman — Wake Forest Baptist Comprehensive Cancer Center
• Study coordinator: Stephanie Bunch
• Email: sbunch@wakehealth.edu
• Phone: 3367165180

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.