Betamethasone vs Dextrose Injections for Trigger Finger

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial compares two ultrasound-guided injections for trigger finger: betamethasone, a corticosteroid, and a dextrose solution. Participants aged 18 to 75 with symptoms for at least four weeks are assigned to receive one of the injections with lidocaine under sterile conditions. The study measures pain on the Numeric Rating Scale as the primary outcome, with secondary outcomes including triggering severity, hand function, grip and pinch strength, and fine motor skills over a 12-week follow-up. The aim is to determine which injection provides greater symptom relief and functional improvement in this condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 75 years
* Clinical diagnosis of trigger finger
* Presence of symptoms for at least 4 weeks

Exclusion Criteria:

* Previous surgery on the affected finger
* Injection treatment to the affected finger within the previous 3 months
* Active local or systemic infection
* Active malignancy
* Active inflammatory rheumatic disease (e.g., rheumatoid arthritis, ankylosing spondylitis, polymyalgia rheumatica, vasculitis)
* Uncontrolled diabetes mellitus and/or uncontrolled hypertension
* Autoimmune connective tissue diseases (e.g., systemic lupus erythematosus, antiphospholipid syndrome, systemic sclerosis, Sjögren syndrome, polymyositis, dermatomyositis, adult-onset Still's disease)
* Coagulopathy that increases the risk of injection procedures
* Pregnancy
* Known allergy or hypersensitivity to lidocaine, betamethasone, or dextrose
* Mental impairment or severe psychiatric disorder that may interfere with study participation or informed consent

Where it's running

• Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Merve Yıldız, MD
• Email: merveyildizdr@gmail.com
• Phone: +905350229993

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Low-Level Laser Therapy for Trigger Finger

  This study tests whether low-level laser therapy can help people with trigger finger see if it reduces pain and improves finger movement.

  Recruiting Dokuz Eylul University · Izmir, Balçova · NCT07753460

• Longitudinal versus transverse A1 pulley incision for trigger finger

  This trial will test whether a straight (longitudinal) or a crease-based (transverse) skin incision leads to better hand function, less pain, and improved scarring after open A1 pulley release in adults with trigger finger.

  Recruiting at 2 sites Washington University School of Medicine · Chicago, Illinois and 1 other locations · NCT07516652

• Comparing a finger splint, paraffin baths, and peloidotherapy for trigger finger

  This tests whether a finger splint, paraffin baths, or peloidotherapy works best to reduce pain and catching in adults 18–75 with a single trigger finger.

  Recruiting Konya Beyhekim Training and Research Hospital · Konya, Konya · NCT07256522

• Ultrasound-guided needle knife release for trigger finger treatment

  This study is testing a new needle procedure using ultrasound to see if it can help people with trigger finger who haven't found relief from other treatments.

  Recruiting Mansoura University Hospital · Al Mansurah, Dakahlia Governorate · NCT06788860

• Comparing treatments for Trigger Finger using shock wave therapy and splints

  This study is testing whether shock wave therapy alone, shock wave therapy with splints, or just splints works best to relieve pain and improve function for people with Trigger Finger.

  Recruiting Hacettepe University · Ankara · NCT06296017

• Treatment for trigger finger using a night orthosis after cortisone injection

  This study tests if wearing a special night splint after a cortisone shot can help people with trigger finger feel better and use their hands more easily.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California and 1 other locations · NCT05837286

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.