Bempedoic acid adherence, persistence, and effect in adults in Italy
Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Bempedoic Acid in Italy
This project will see how well bempedoic acid works and how consistently adults with high cholesterol in Italy take it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Federico II University Academic / other |
| Locations | 1 site (Naples, Napoli) |
| Trial ID | NCT07374861 on ClinicalTrials.gov |
What this trial studies
This multicenter observational project will follow adults in Italy who are already being treated with bempedoic acid to document medication adherence, persistence, and changes in lipid levels in routine care. Investigators will collect clinical records, laboratory lipid measurements, and adherence information such as prescription refills or patient reports. The study excludes people under 18 or over 80 and requires informed consent from participants. Data will be analyzed to describe real-world persistence over time and the associated impact on cholesterol control.
Who should consider this trial
Good fit: Adults aged 18–80 in Italy who are currently taking bempedoic acid and willing to give informed consent.
Not a fit: People not taking bempedoic acid, individuals under 18 or over 80, or those who decline consent are not eligible and will not benefit from this study's findings.
Why it matters
Potential benefit: If successful, the findings could help clinicians understand real-world adherence and effectiveness of bempedoic acid and guide strategies to improve cholesterol control.
How similar studies have performed: Randomized trials have shown bempedoic acid lowers LDL cholesterol and improves outcomes, while real-world adherence studies for this drug are limited, so this project adds observational data from routine care.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients under Bempedoic acid treatment Exclusion Criteria: * Age \< 18 years o \> 80 years * Patients who refuse to participate and to sign informed consent
Where this trial is running
Naples, Napoli
- Federico II University of Naples, Department of Advanced Biomedical Sciences — Naples, Napoli, Italy (Recruiting)
Study contacts
- Study coordinator: Pasquale Perrone Filardi
- Email: fpperron@unina.it
- Phone: +39081/7462224
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.