Aztreonam‑avibactam for MBL-producing CRE infections in hospitalized adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project will collect real‑world treatment and outcome data from Chinese hospitals on adults with confirmed cIAI or HAP/VAP caused by MBL-producing carbapenem‑resistant Enterobacterales who received aztreonam‑avibactam for at least 24 hours. Investigators will record patient characteristics, infection details, microbiology, antibiotic use, hospital length of stay, and clinical outcomes. No experimental interventions are assigned; the study documents care given in routine practice. The aim is to describe how the drug is being used and how patients fare in typical hospital settings in China.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\. Age 18 years or older 2. Hospitalized with a diagnosis of confirmed cIAI or HAP/VAP 3. Confirmed infection with MBL-producing CRE 4. Received on label use of ATM-AVI treatment for ≥24 hours 5. Informed consent will be obtained or waived.

Exclusion Criteria:

* 1\. Confirmed or suspected infection caused by Gram-negative species not expected to respond to ATM-AVI 2. Currently enrolled in an interventional clinical tria

Where it's running

• The First Affiliated Hospital of Nanchang University
  Nanchang, Jiangxi, China Recruiting
• Sir Run Run Shaw Hospital
  Hangzhou, Zhejiang, China Not yet recruiting

Study contacts

• Study coordinator: Yunsong Yu, PhD
• Email: yvys119@zju.edu.cn
• Phone: 86-13805790432

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.