Ayurvedic vegetarian diet for primary hypothyroidism
Official title: Ayurvedic Diet as a Supplement to Levothyroxine Treatment of Myxedema
Run by University of Copenhagen · NCT07323706 · Data updated 2026-11-12
This study will try an Ayurvedic vegetarian diet alongside usual levothyroxine to see if it helps adults with primary hypothyroidism who have the Vishamagni digestive type.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 88 (estimated) |
| Sponsor | University of Copenhagen Academic / other |
| Locations | 2 sites (Copenhagen, Frederiksberg and 1 other locations) |
| Status | Recruiting |
| Started | October 1, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2029 |
| Registry record updated | January 7, 2026 |
| Trial ID | NCT07323706 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with primary hypothyroidism on stable levothyroxine for at least six months who are identified as having the Vishamagni digestive type and willing to follow an Ayurvedic vegetarian diet.
✕Probably not a fit
People with secondary or central hypothyroidism, unstable thyroid medication, concurrent prescription medications, prior Ayurvedic treatment, or who are pregnant or breastfeeding are unlikely to be eligible or to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares a prescribed Ayurvedic vegetarian diet to participants' habitual diet as an add-on to standard levothyroxine treatment. Eligible participants are adults with primary hypothyroidism on unchanged medication for at least six months and classified as the Vishamagni digestion type, while pregnant or lactating people, those on other prescription drugs, or with prior Ayurvedic treatment are excluded. The intervention aims to alter dietary patterns and the gut microbiome to reduce persistent symptoms such as fatigue, weight gain, and cognitive complaints despite normalized thyroid hormone levels. Study visits are conducted at the University of Copenhagen and an Ayurvedic clinic in Sorø, with symptom and thyroid-related outcomes tracked over the intervention period.
Why it matters
Potential benefit: If successful, the diet could reduce persistent symptoms and improve quality of life for people whose thyroid hormone levels are controlled by medication but who still feel unwell.
How similar studies have gone: Some dietary and microbiome-focused interventions have shown promise for metabolic and thyroid-related health, but using a formal Ayurvedic diet as an adjunct to levothyroxine remains largely untested in rigorous clinical trials.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosed with primary hypothyroidism * primary digestive type Vishamagni * under medical treatment for hypothyroidism * unchanged medication for the past 6 months Exclusion Criteria: * previous Ayurvedic treatment * prescription drugs other than medication for hypothyroidism * pregnancy * lactating women.
Where it's running
-
Department of Nutrition, Exercise and Sports
Copenhagen, Frederiksberg, Denmark Recruiting -
Ayuvedic Clinic, Sorø
Sorø, Denmark Recruiting
Study contacts
- Principal investigator: Mette Westerholt, MSc — Ayus
- Study coordinator: Jens Rikardt Andersen, MD, MPA
- Email: jra@nexs.ku.dk
- Phone: 0045 35332504
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.