Automated freezing of eggs and embryos
Official title: Automation of Oocyte and Embryo Vitrification: a Pilot Study
Run by Conceivable Life Sciences · NCT07197983 · Data updated 2026-11-12
This study will test whether a new automated system called PRESERVE-CR can freeze eggs and embryos as effectively as manual vitrification by embryologists for people having IVF/ICSI.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 38 Years |
| Sex | All |
| Enrollment | 125 (estimated) |
| Sponsor | Conceivable Life Sciences Industry-sponsored |
| Locations | 1 site (Manchester) |
| Status | Recruiting |
| Started | October 14, 2025 |
| Main results expected | June 30, 2026 |
| Study ends | June 30, 2026 |
| Registry record updated | November 20, 2025 |
| Trial ID | NCT07197983 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are people undergoing IVF/ICSI at CARE Fertility Manchester with BMI 20–35 kg/m² and AMH ≥1.5 ng/mL who do not require surgical sperm retrieval.
✕Probably not a fit
People with low ovarian reserve, those requiring surgical sperm retrieval, or those treated outside the trial criteria or site are unlikely to receive benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial directly compares a prototype automated vitrification device (PRESERVE-CR) with the clinic's standard manual vitrification performed by experienced embryologists. People undergoing IVF/ICSI at CARE Fertility Manchester who consent will have some eggs or embryos frozen using either the automated system or the manual method. The study will measure preservation outcomes such as survival and quality after warming, along with procedure time and operator variability. Results will show whether automation can match manual performance while providing more standardized and efficient workflows.
Why it matters
Potential benefit: If successful, the automated system could standardize freezing outcomes, reduce training and staffing burdens, lower costs, and help make fertility preservation more accessible.
How similar studies have gone: Automated vitrification approaches are relatively novel with limited published clinical comparison data, while manual vitrification by experienced embryologists remains the established standard.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * BMI: Between 20-35 kg/m² * Ovarian Reserve: Anti-Müllerian Hormone (AMH) ≥1.5 ng/mL Exclusion Criteria: * Low ovarian reserve * Surgical sperm retrieval required
Where it's running
-
CARE Fertility
Manchester, United Kingdom Recruiting
Study contacts
- Study coordinator: Giuseppe Silvestri, PhD
- Email: giuseppe@conceivable.life
- Phone: +44 7990960731
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.