Automated blood exchange for sickle cell disease treatment in Egypt
Assessment of Implementation of the Automated Erythrocytapheresis in the Outcome of Egyptian Sickle Cell Disease Patients: Single Center Experience
This study is testing whether an automated blood exchange method can help people with sickle cell disease in Egypt have fewer complications compared to traditional blood transfusions.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 2 Years to 30 Years |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Non-US) |
| Trial ID | NCT03903289 on ClinicalTrials.gov |
What this trial studies
This study evaluates the implementation of automated erythrocytapheresis in patients with sickle cell disease at a single center in Egypt. The research aims to assess how this automated red cell exchange procedure can improve patient outcomes by reducing complications associated with sickle cell disease. The study will compare the effectiveness of automated erythrocytapheresis to manual red cell exchange and simple red cell transfusions. By focusing on a specific population, the study seeks to provide insights into the management of sickle cell disease in a resource-limited setting.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 2 to 30 years diagnosed with sickle cell disease.
Not a fit: Patients with other hemoglobinopathies or those younger than two years will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the management and outcomes of patients with sickle cell disease.
How similar studies have performed: While automated erythrocytapheresis has been used in other settings, this specific implementation in Egypt is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient with sickle cell disease (HbS with other variant hemoglobin) * Age from 2-30y old Exclusion Criteria: Patients with other hemoglobinopathy Patients younger than two years
Where this trial is running
Cairo, Non-US
- Faculty of Medicine, Ain Shams University — Cairo, Non-US, Egypt (Recruiting)
Study contacts
- Principal investigator: Fatma Solima SE Ebeid, MD — Faculty of Medicine, Ain Shams university
- Study coordinator: Fatma SE Ebeid, MD
- Email: dr.fatma_ebeid@yahoo.com
- Phone: 01095569596
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.