Automated applanation tonometry to measure eye pressure
Automated Applanation Tonometry - Updated
NA · Duke University · NCT07298356
We will test two new automated, portable ways to measure eye pressure in adults with glaucoma or suspected glaucoma and see how they compare to standard methods.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Duke University (other) |
| Locations | 1 site (Durham, North Carolina) |
| Trial ID | NCT07298356 on ClinicalTrials.gov |
What this trial studies
This is a prospective comparison of two investigational applanation methods against Goldmann applanation tonometry (GAT) and pneumotonometer readings in adults presenting for routine eye care. After informed consent, intraocular pressure measurements will be taken by standard GAT, a pneumotonometer, a fixed-force GAT with a CMOS camera recording the mire diameter, and an upright applanating prototype. The fixed-force approach uses a preset GAT force while video captures mire size for automated calculation of IOP, and the study will compare reproducibility and agreement across methods. The goal is to determine whether the investigational methods deliver more objective, repeatable, and portable IOP measurements than current clinical standards.
Who should consider this trial
Good fit: Adults (18 and older) presenting for a routine eye exam with glaucoma or suspected glaucoma who can give informed consent and do not have excluded ocular surface conditions are the intended participants.
Not a fit: Patients with corneal scarring, active eye infection, ocular surface trauma, or anyone unable to travel to the study site are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, the methods could provide more objective, repeatable, and portable eye pressure measurements that improve monitoring and management of glaucoma.
How similar studies have performed: Similar fixed-force and smartphone-based imaging approaches have been piloted and show promise but remain relatively novel and not yet widely adopted in clinical practice.
Eligibility criteria
Show full inclusion / exclusion criteria
Criteria: Inclusion Criteria: * Presenting for a routine eye exam * ≥ 18 years of age * Able and willing to give consent Exclusion Criteria: * History of corneal scarring * Active infection of the eye * Ocular surface trauma or infection
Where this trial is running
Durham, North Carolina
- Duke Eye Center — Durham, North Carolina, United States (RECRUITING)
Study contacts
- Principal investigator: Joanne Wen, MD — Duke Eye Center
- Study coordinator: Sarah Jones
- Email: sarah.jones1@duke.edu
- Phone: 919 681 6584
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Glaucoma, Glaucoma, Suspect