Autologous Free Dermal Graft Support in Vertical Scar Breast Reduction
Official title: Effect of Autologous Free Dermal Graft Use on Lower Pole Stability in Superior Pedicle Vertical Scar Reduction Mammaplasty: A Prospective Comparative Cohort Study
Run by Cumhuriyet University Hospital · NCT07657962 · Data updated 2026-11-12
This study tests whether using a patient’s own skin graft to support the lower pole helps keep the breast shape after a vertical scar breast reduction.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | Women only |
| Enrollment | 70 (estimated) |
| Sponsor | Cumhuriyet University Hospital Academic / other |
| Locations | 1 site (Sivas, Sivas) |
| Status | Recruiting |
| Started | August 24, 2026 |
| Main results expected | February 28, 2028 |
| Study ends | February 28, 2028 |
| Registry record updated | August 25, 2026 |
| Trial ID | NCT07657962 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 18–65 planning a primary bilateral reduction mammaplasty using the superior pedicle vertical scar technique, with willingness to follow 6 months of postoperative follow-up.
✕Probably not a fit
Patients who do not experience lower-pole elongation or who have different anatomy or healing patterns may not benefit from the graft.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort study compares two groups of women undergoing primary bilateral superior pedicle vertical scar reduction mammaplasty: with and without autologous free dermal graft support. Participants are followed for 6 months with standard breast measurements, photos, and a satisfaction survey. The goal is to see if the dermal graft helps prevent lower-pole elongation and pseudoptosis over time. It is a prospective, single-center effort conducted at Cumhuriyet University Hospital in Sivas. The graft is a de-epithelialized dermal tissue placed in the lower pole, intended as autologous support without vascular pedicles or synthetic materials.
Why it matters
Potential benefit: If successful, this approach could provide a simple, autologous option to improve long-term breast shape after reduction.
How similar studies have gone: Other internal support methods for long-term shape stability have shown variable results; this specific autologous dermal graft approach is being evaluated for feasibility and potential benefit.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female participants aged 18 to 65 years * Planned primary bilateral reduction mammaplasty * Planned use of the superior pedicle vertical scar technique * Willingness to attend at least 6 months of postoperative follow-up * Ability to provide written informed consent * Consent for standardized medical photography and clinical breast measurements Exclusion Criteria: * Previous breast surgery * Oncoplastic breast reduction * Unilateral reduction mammaplasty * Use of a pedicle technique other than the superior pedicle * Use of a scar pattern other than the vertical scar pattern * Presence of a systemic condition expected to significantly impair wound healing * Active smoking within the last 6 weeks before surgery * Incomplete 6-month follow-up data for the primary outcome analysis
Where it's running
-
Sivas Cumhuriyet University
Sivas, Sivas, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Murat Çelik, Assistant Professor — Cumhuriyet University
- Study coordinator: Murat Çelik, Assistant Professor
- Email: mucetr@gmail.com
- Phone: +905546902104
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.