Auditory and touch stimulation to help people wake after general anesthesia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial applies non-drug interventions—verbal stimulation, tactile shoulder tapping, and shoulder shaking—during the emergence phase from general anesthesia for adult patients undergoing laparoscopic abdominal surgery. EEG monitoring and clinical recovery measures such as time to eye opening, extubation, and standardized recovery scores are used to track the pace and quality of emergence. Participants meeting inclusion criteria (age 18–65, ASA I–III, BMI ≤30) receive these interventions while patients with neurological disorders, significant comorbidities, or auditory impairments are excluded. The approach tests whether targeted sensory inputs can modulate neural pathways involved in restoring consciousness and improve postoperative recovery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Adult patients aged 18 to 65 years, with American Society of Anesthesiologists (ASA) physical status I-III;
2. Scheduled for laparoscopic abdominal surgery, including gastric, colorectal, or biliary procedures;

Exclusion Criteria:

1. ASA physical status IV;
2. Body mass index (BMI) greater than 30 kg/m²;
3. Presence of underlying neurological dysfunction, cognitive impairment, or auditory disorders;
4. Neurological, cardiovascular, hepatic, or renal dysfunction;
5. Current use of antipsychotic medications or a history of psychiatric illness;
6. History of alcohol abuse or substance dependence;
7. Exposure to general anesthesia or sedation within 1 month prior to surgery;
8. Presence of intracranial implants or a history of epilepsy;
9. Known allergy to any drugs used in this study;
10. Preoperative use of electronic hearing aids or implanted auditory devices;
11. Refusal to participate in the study.

Where it's running

• West China Hospital of Sichuan University
  Chengdu, Sichuan, China Recruiting

Study contacts

• Study coordinator: Prof. Du
• Email: duguizhi@scu.edu.cn
• Phone: +86 18980602213

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.