Atrial dyssynchrony to predict arrhythmias after cardiovascular surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Patients scheduled for non-mitral cardiovascular surgery who are in sinus rhythm will have a preoperative Doppler echocardiogram with two-dimensional speckle-tracking atrial strain and, when possible, 3D left atrial ejection fraction measurement. Images are obtained in left lateral decubitus with 3 consecutive beats recorded in forced expiration using a Philips EPIC CVx system and analyzed in 2- and 4-chamber views to quantify intra- and inter-atrial dyssynchrony, indexed left atrial volume, and left ventricular ejection fraction by Simpson biplane. Participants are followed during the postoperative hospital stay to record occurrences of atrial fibrillation. The protocol excludes patients with prior atrial fibrillation, mitral or tricuspid valve surgery, congenital heart disease or cardiac tumors, emergency cardiac surgery, or an inadequate echocardiographic window.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with criteria for non-mitral cardiovascular surgery, in sinus rhythm, and who gave informed consent to participate in the study.
* Absence of atrial fibrillation upon hospital admission for surgery.

Exclusion Criteria:

* Surgery of the mitral or tricuspid valve.
* History of previous atrial fibrillation.
* History of congenital heart disease or cardiac tumors.
* Emergency surgery of the heart
* Pour echocardiographic window

Where it's running

• Clínica de Cuyo
  Mendoza, Mendozz, Argentina Recruiting

Study contacts

• Study coordinator: Francisco Sánchez, PhD
• Email: fsanchez@fcm.uncu.edu.ar
• Phone: +5492614135000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.