At-home therapy using the Vivistim System for stroke recovery

Vagus Nerve Stimulation (VNS) During Rehabilitation Using the Vivistim System®: Post-Market Study for Stroke Rehabilitation in a Home Environment for Subjects With Chronic Stroke (VNS-REHAB At-Home)

Observational MicroTransponder Inc. · NCT05691023

This study is testing whether at-home therapy using the Vivistim System can help people recover better from arm weakness after a stroke compared to regular in-clinic therapy.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages19 Years and up
SexAll
SponsorMicroTransponder Inc. Industry-sponsored
Locations1 site (Chicago, Illinois)
Trial IDNCT05691023 on ClinicalTrials.gov

What this trial studies

This observational study involves up to 150 participants who have been implanted with the Vivistim System, focusing on at-home rehabilitation therapy for upper extremity motor deficits following ischemic stroke. Participants will receive therapy from mobile therapists in their homes, combined with self-activated vagus nerve stimulation (VNS) for enhanced recovery. The study consists of two stages: an acute treatment phase lasting up to 18 weeks and a long-term follow-up phase of up to two years, assessing the effectiveness of this home-based approach compared to traditional in-clinic therapy.

Who should consider this trial

Good fit: Ideal candidates are adults who have been implanted or are scheduled to be implanted with the Vivistim System and can receive therapy at home.

Not a fit: Patients under 18 years old or pregnant women will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve motor function and recovery outcomes for stroke patients in the comfort of their homes.

How similar studies have performed: While the use of VNS in rehabilitation is a novel approach, similar studies have shown promise in enhancing recovery outcomes for stroke patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient implanted or scheduled to be implanted commercially with the Vivistim System.
* Patient assessed as able to receive therapy in their home.

Exclusion Criteria:

* Patient aged 18 or younger.
* Pregnant women

Where this trial is running

Chicago, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ischemic StrokeUpper Extremity Problem
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.