Associations Between Multidimensional Phenotypes and Growth and Development
Official title: A Study on Associations Between Multidimensional Human Phenotypic Traits and Human Growth and Development
Run by Nanfang Hospital, Southern Medical University · NCT07857798 · Data updated 2026-11-12
This study tests how external phenotypic traits like fingerprints, foot shape, and facial features relate to musculoskeletal growth and development in adults and older youth.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Nanfang Hospital, Southern Medical University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | September 2026 |
| Main results expected | September 2027 |
| Study ends | September 2027 |
| Registry record updated | October 19, 2026 |
| Trial ID | NCT07857798 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18–60 who can consent and complete all phenotypic assessments without a history of surgeries or conditions affecting musculoskeletal morphology.
✕Probably not a fit
Individuals with prior surgeries or congenital/developmental conditions affecting limbs or musculoskeletal morphology may have limited relevance to study aims and potential benefits.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study plans to enroll 500 participants aged 18 to 60 to explore links between diverse phenotypic traits and musculoskeletal growth. Non-invasive assessments will include fingerprint imaging, 3D foot scanning, facial and tongue imaging, and standard anthropometric and joint examinations. Musculoskeletal development will be evaluated through measures such as plantar arch morphology, lower-limb alignment, range of motion, and Beighton joint mobility. Data will be analyzed to identify associations between phenotypic characteristics and growth-related musculoskeletal features, with secondary aims exploring combinations of traits that may correspond to specific patterns of development.
Why it matters
Potential benefit: If successful, findings could improve understanding of how external phenotypes relate to musculoskeletal development and potentially inform non-invasive screening approaches.
How similar studies have gone: Prior research has explored associations between dermatoglyphics and growth features, but this approach of integrating multiple phenotypic modalities is relatively novel and exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18 to60 years. * Able to understand the study procedures and provide informed consent. * Willing and able to complete the required phenotypic assessments and measurements. Exclusion Criteria: * History of surgery that may affect musculoskeletal morphology or function. * Known congenital or developmental disorders that may affect physical growth, limb development, or musculoskeletal morphology. * Unable to complete the required study assessments.
Where it's running
-
Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China Recruiting
Study contacts
- Study coordinator: Chao Chen
- Email: chenchao@smu.edu.cn
- Phone: 86+13580348819
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.