Assessing visual frailty in older adults with age-related macular degeneration
Official title: Seeing Through Their Eyes - Towards Defining Visual Frailty in Ageing
Run by University of Edinburgh · NCT06604104 · Data updated 2026-11-12
This study is trying to see if a new tool can help understand how vision problems affect older adults with advanced age-related macular degeneration and their overall health.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | University of Edinburgh Academic / other |
| Locations | 2 sites (Edinburgh, Scotland and 1 other locations) |
| Status | Recruiting |
| Started | April 9, 2025 |
| Main results expected | January 11, 2027 |
| Study ends | February 2027 |
| Registry record updated | March 4, 2026 |
| Trial ID | NCT06604104 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are residents of Scotland aged 60 and above with a known diagnosis of advanced Age-related Macular Degeneration who have been receiving treatment for at least six months.
✕Probably not a fit
Patients who cannot speak or read English, have undergone invasive ocular surgery recently, or cannot provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to define and assess visual frailty in individuals aged 60 and above diagnosed with advanced Age-related Macular Degeneration (AMD). It will pilot a visual frailty assessment tool that evaluates visual acuity, reading performance, functional status, mental health, and systemic co-morbidities. Over three years, the study will involve literature review, participant recruitment, and validation of the assessment tool, with data collected from patients at various NHS Lothian facilities. The study seeks to establish the relationship between visual frailty and other health factors in the ageing population.
Why it matters
Potential benefit: If successful, this study could lead to improved assessment and management of visual frailty, enhancing the quality of life for older adults with AMD.
How similar studies have gone: While the concept of visual frailty is emerging, this specific approach to assessing it in the context of AMD is novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants should be residents of Scotland aged 60 years and above with a known diagnosis of advanced AMD. * The patients should be receiving treatment from Princess Alexandra Eye Pavilion (PAEP) for at least 6 months and should be responding positively to the treatment. This is to rule out poor results due to either not receiving medication or non-compliance. * The participants should be able to provide informed consent before taking part in the study. Exclusion Criteria: * Participants who cannot speak and read English language will not be included in this pilot study. However, non-English speakers will be included in the future together with interpreters at the validation phase of the developed tool. * Participants who have undergone invasive ocular surgery like cataract extraction in their previous visit. * The potential participants who fail to provide or do not provide informed consent will not be included in the study.
Where it's running
-
Anne Rowling Clinic
Edinburgh, United Kingdom Recruiting -
The Princess Alexandra Eye Pavilion
Edinburgh, Scotland, United Kingdom Not yet recruiting
Study contacts
- Principal investigator: Peter Cackett — Princess Alexandra Eye Pavilion
- Study coordinator: Godfrey Wanok, BSc (Hons) Optom; MSc PCO
- Email: W.Godfrey@sms.ed.ac.uk
- Phone: +447442374789
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.