Assessing vision in preverbal children with eye conditions

Determination of the Validity of a Questionnaire to Assess the Visual Function of Preverbal Children with Operable Bilateral Ocular Pathologies

Not applicable Interventional Fondation Ophtalmologique Adolphe de Rothschild · NCT04428541

This study is testing a new questionnaire to help doctors understand how well preverbal children with eye problems can see, so they can make better decisions about their treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment150 (estimated)
Ages0 Months to 36 Months
SexAll
SponsorFondation Ophtalmologique Adolphe de Rothschild Research network
Locations1 site (Paris)
Trial IDNCT04428541 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate a newly developed questionnaire designed to assess the visual function of preverbal children suffering from operable bilateral ocular pathologies. The questionnaire was created based on existing literature and expert opinions in the field of pediatric ophthalmology. The primary goal is to determine both the internal and external validity of this tool, which is crucial for making informed surgical decisions regarding treatment timing. By quantifying visual function in young children who cannot verbally communicate their vision status, the study seeks to improve clinical outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 0 to 36 months diagnosed with operable bilateral ocular pathologies.

Not a fit: Patients with unilateral ocular pathology or those who are verbal and can express their vision will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better timing for surgical interventions in young children with eye conditions, potentially improving their visual outcomes.

How similar studies have performed: While there may be limited studies specifically targeting this age group with similar methodologies, the approach of using questionnaires for assessing visual function in children is a recognized area of interest in pediatric ophthalmology.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Common to the three groups:

* Patient aged 0 to 36 months
* Diagnosis of known ocular pathology

For patients targeted by the questionnaire:

- Patient with operable bilateral ocular pathology

For negative controls:

- Patient without ocular pathology inducing a decrease in vision

For positive controls:

* Patient with inoperable bilateral ocular pathology
* Patient without light perception

Exclusion Criteria:

* Patient with unilateral ocular pathology
* Verbal patients (able to express themselves through speech)

Where this trial is running

Paris

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Eye DiseasesVision DisordersQuestionnaire DesignChildrenInfant
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.